UniProt Accession

 PGFS_MOUSE; Q9DB60 

Genbank Protein ID

 AK005188; AL607032; BC030453 

Genbank Nucleotide ID

 BAB23870.1; CAM15790.1; AAH30453.1 

Protein Name

 Prostamide/prostaglandin F synthase 

Protein Synonyms/Alias

 Prostamide/PG F synthase; Prostamide/PGF synthase 

Gene Name

 Fam213b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
101	DESKQIYKELGFKRY	ubiquitination	[1]
120	ILPAALGKPVRDVAS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha). 

Sequence Annotation

 MOD_RES 108 108 Phosphotyrosine.  

Keyword

 Complete proteome; Cytoplasm; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; NADP; Oxidoreductase; Phosphoprotein; Prostaglandin biosynthesis; Prostaglandin metabolism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 201 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0047017; F:prostaglandin-F synthase activity; ISO:MGI.
 GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS