| Tag | Content |
|---|
| CPLM ID | CPLM-016663 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sodium/hydrogen exchanger 9 |
Protein Synonyms/Alias | Na(+)/H(+) exchanger 9; NHE-9; Solute carrier family 9 member 9 |
Gene Name | Slc9a9 |
Gene Synonyms/Alias | Nhe9 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 617 | SSGQTPGKENIYEGD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell (By similarity). |
Sequence Annotation | |
Keyword | Antiport; Complete proteome; Endosome; Ion transport; Membrane; Reference proteome; Sodium; Sodium transport; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 644 AA |
Protein Sequence | MAGQLRFTSG KDEDHFQHQG AVELLAFNFL LILTILTIWL FKNHRFRFLH ETGGAMVYGL 60
IMGLILRYAT APTDIDSGTV YNCGNLFFSP STLLVNITDQ VYEYKYQREI NQHNISPHQG 120
NAILEKMTFD PEIFFNVLLP PIIFHAGYSL KKRHFFQNLG SILTYAFLGT AISCVVIGLI 180
MYGFVKAMVH AGQLKSGDFH FTDCLFFGSL MSATDPVTVL AIFHELHVDP DLYTLLFGES 240
VLNDAVAIVL TYSISIYSPK ENPNAFDTAA FFQSVGNFLG IFAGSFAMGS AYAVVTALLT 300
KFTKLREFPM LETGLFFLLS WSAFLSAEAA GLTGIVAVLF CGVTQAHYTY NNLSSDSKLR 360
TKQLFEFMNF LAENVIFCYM GLALFTFQNH IFNALFILGA FLAIFVARAC NIYPLSFLLN 420
LGRKQKIPWN FQHMMMFSGL RGAIAFALAI RNTESQPKQM MFTTTLLLVF FTVWVFGGGT 480
TPMLTWLQIR VGVDLDESLK EEPSSQQEAN KLDKNMTKTE SAQLFRMWYG FDHKYLKPIL 540
THSGPPLTTT LPAWCGPVSR LLTSPQAYGE QLKEDDVECI VNQDELAMNY QEQSPSPSSP 600
TTKLALDQKS SGQTPGKENI YEGDLGLGGY DLKLEQTRGQ PQMD 644 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0055037; C:recycling endosome; IEA:Compara. GO:0015385; F:sodium:hydrogen antiporter activity; IEA:InterPro. GO:0006885; P:regulation of pH; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |