| Tag | Content |
|---|
| CPLM ID | CPLM-032447 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | CLCN3 protein |
Protein Synonyms/Alias | H(+)/Cl(-) exchange transporter 3 |
Gene Name | CLCN3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 440 | LNTSELIKELFTDCG | ubiquitination | [1] | | 681 | GFPVIMSKESQRLVG | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 801 AA |
Protein Sequence | MVTLQLGESH YVVQAGLQLL GSSNPPALAS QVAEITGTHY TMTNGGSINS STHLLDLLDE 60
PIPGVGTYDD FHTIDWVREK CKDRERHRRI NSKKKESAWE MTKSLYDAWS GWLVVTLTGL 120
ASGALAGLID IAADWMTDLK EGICLSALWY NHEQCCWGSN ETTFEERDKC PQWKTWAELI 180
IGQAEGPGSY IMNYIMYIFW ALSFAFLAVS LVKVFAPYAC GSGIPEIKTI LSGFIIRGYL 240
GKWTLMIKTI TLVLAVASGL SLGKEGPLVH VACCCGNIFS YLFPKYSTNE AKKREVLSAA 300
SAAGVSVAFG APIGGVLFSL EEVSYYFPLK TLWRSFFAAL VAAFVLRSIN PFGNSRLVLF 360
YVEYHTPWYL FELFPFILLG VFGGLWGAFF IRANIAWCRR RKSTKFGKYP VLEVIIVAAI 420
TAVIAFPNPY TRLNTSELIK ELFTDCGPLE SSSLCDYRND MNASKIVDDI PDRPAGIGVY 480
SAIWQLCLAL IFKIIMTVFT FGIKVPSGLF IPSMAIGAIA GRIVGIAVEQ LAYYHHDWFI 540
FKEWCEVGAD CITPGLYAMV GAAACLGGVT RMTVSLVVIV FELTGGLEYI VPLMAAVMTS 600
KWVGDAFGRE GIYEAHIRLN GYPFLDAKEE FTHTTLAADV MRPRRNDPPL AVLTQDNMTV 660
DDIENMINET SYNGFPVIMS KESQRLVGFA LRRDLTIAIE SARKKQEGIV GSSRVCFAQH 720
TPSLPAESPR PLKLRSILDM SPFTVTDHTP MEIVVDIFRK LGLRQCLVTH NGRLLGIITK 780
KDILRHMAQT ANQDPASIMF N 801 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |