Tag | Content |
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CPLM ID | CPLM-041944 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase TTC3 |
Protein Synonyms/Alias | Tetratricopeptide repeat domain 3, isoform CRA_b |
Gene Name | Ttc3 |
Gene Synonyms/Alias | mCG_19601 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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470 | DLKSILEKQFSKSSR | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Metal-binding; Reference proteome; Repeat; TPR repeat; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1979 AA |
Protein Sequence | MDDFAEGGLS LADDILLEDY PYEDDCICTP DFTTDDYVRV TQLYYEGVGM QYKDYAQSEK 60 NLEYDICNIW CSKPLSILQD YCDAIKLYIF WPLLFQHQHS SIISRLHPCV EAIRSRAAEI 120 SLKKLQHLEL MEDIVDLAKK VANDSFLIEG LLKIGYKIEN KILAMEDALN WIKYTGDVTI 180 LPKLGSVDNC WPMLSIFFTE YKYHITRVVT ENCNLLEEFR RHSCMQCVKQ GELMKMRGNE 240 EFSKEKFEIA VIYYTRAIEY RPENHLLYGN RALCFLRMGQ FRNALSDGKR AIVLKNTWPK 300 GHYRYCDALC MLGEYDWALQ ANIKAQKLCK NDPEGIKDLI QQHVKLQKQI EDLQGRTSNK 360 NPIKAFYESR AYIPRNSSAP AFRTSLNFVE TERGFRKTKY KMANGGDQNQ KVADEALKGD 420 DCDCHPEFLP PPSQPPRHKG KQKSRNNESE KPSSNSEVSL QVDLKSILEK QFSKSSRAAH 480 QDFANIMKML RSLIQDGYTA LLEQRCRSAA QAFTELLNGL DPQKIKQLNL AMINYVLVVY 540 GLAVSLLGIG RPEELSEAEN QFKRIIEHYP NEGLDCLAYC GIGKVYLKKN RFLEALNHFE 600 KAKTLISRLP GILTWPTSNV IIEESKPEKV KVMLEKFVEE CKFPPVPDAV CCYQKCRGYS 660 KIQIYLTDPD FKGFIRISCC QYCKVEFHMN CWKKLKTTTF NDKIDKDFLQ GICLTPDCEG 720 IISKIIIYSS GGQVKCEFEH KVIKEKVPSR PVLKQKCSSL EKLRLKEDKK LKRKIQKQEA 780 KKLAQERMEE DLRESNPPKN EEPEETSDSA QRCQFLDDRI LQCIKQNADK IKSVVLNTST 840 LLKELLSWKV LSTEDYTTCF SSKNFVHEAV DYVIGHLIQE KNRVKTRIFL HVLSELKELD 900 PKLAPWIQRL NSFGLDAIGP FFTRYGASLK ELDFHVVTVL WDEKYGHKLG SIEGKQLDYF 960 FEPASAMEAR CLIWLLEEHR DKFPALHSAL DEFFDIMDSR CTVLRKQDSD EMPFGCIKVK 1020 NKGKKKKPKD SKPMLVGSGA ASVAPSSEAV TPEDHSRRNS DSAGPFAVPD HLRQDVEEFE 1080 ALYDQHSSEY VVRNKKLWDI NPKQKCSTLY DYFSQLLEEH GPLDMSDRMF SEEYEFFPEE 1140 TRQILEKAGG LKSFLLGCPR FVVIDNCIAL KKVASRLKKK RKKKNMKAKV EDISKTGEYL 1200 RVKLPLNPTA REFQPDVKSE ALSEDVKSIP GPADSSTLAA EDLKAQLDSD SSSGSASEDS 1260 RLEVASPDSP TPLCEDASPS PTPAPEEAKP TYWAQSHLVT GFCTYLPFQG FGITQRPAYI 1320 NMVPSLSQFT SIYTPLANIS SEYPMQRSMP VVPSFVASNR ADENAAAYFE SPNLNTEHDS 1380 GDHMASETQI LEDTLGVCVR SQGSAADADP ALSEPEGNSE HSGSSDSLWE ASLENVSGTT 1440 DAPAAPSVAI QVSRSMVHQE VNTEPYEPFE TQQGDLSQKE KECHLLREQL KVACENCEQI 1500 ELRSSQEIKD LEEKLQRHTE ENKISKTELD WFLQDLDREI KKWQQEKKEI QERLKALKKK 1560 IKKVINTSEM PAQKNDGFDK ECEPHPDQSL GFSSALTDEK TKVEESVRKG KELYEESHQR 1620 AVAAEVSVLE NWKEREVCKL QGVASQSEAY LKSLKLMSSD SATYPDVEYD ILSWESFLST 1680 VREEIESKKS QFEEHIKAIK NGSRLSDLSS VQLSEVSFPG CSTIHPQFLS ESSGHEDPGL 1740 VACVDSMTGA VLNDPYMDSA SGCPEEVPEL SLGSPTHQPE VTQQLELKGA SQVSPSEQSP 1800 EADEKLSGQA TRSSQSPKKP SNSIIEHLSV IFPCYTSTEL AGFIKKVRNK TKNSFSGLTI 1860 EEIVEKVTEH IVDEQKKKKP NPGKDKKTSE AHSAASVAKS SQSPPLAAAG PSARTKGQKK 1920 DDVPAPDGNS CEICHEIFKS KNMRVLKCGH KFHKGCFKQW LKGQSTCPTC GSSDLLSEE 1979 |
Gene Ontology | GO:0005739; C:mitochondrion; IEA:Compara. GO:0005634; C:nucleus; IEA:Compara. GO:0005773; C:vacuole; IDA:MGI. GO:0004842; F:ubiquitin-protein ligase activity; IEA:Compara. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0010771; P:negative regulation of cell morphogenesis involved in differentiation; IDA:MGI. GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI. GO:0070936; P:protein K48-linked ubiquitination; IEA:Compara. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |