UniProt Accession

 CRIP2_HUMAN; P52943; A1A4U1; B7Z6C0; E9PD13 

Genbank Protein ID

 D42123; U36190; BT019911; AK300092; AK315757; AL928654; BC000434; BC001931; BC034151; BC128101 

Genbank Nucleotide ID

 BAA07703.1; AAB03194.1; AAV38714.1; BAH13206.1; BAG38110.1; AAH00434.1; AAH01931.1; AAH34151.1; AAI28102.1 

Protein Name

 Cysteine-rich protein 2 

Protein Synonyms/Alias

 CRP-2; Protein ESP1 

Gene Name

 CRIP2 

Gene Synonyms/Alias

 CRP2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
23	EKVSSLGKDWHKFCL	acetylation	[1]
138	KKVYFAEKVTSLGKD	acetylation	[2]

Reference

 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 

Functional Description

  

Sequence Annotation

 DOMAIN 5 57 LIM zinc-binding 1.
 DOMAIN 126 178 LIM zinc-binding 2.
 MOD_RES 138 138 N6-acetyllysine.  

Keyword

 3D-structure; Acetylation; Alternative splicing; Complete proteome; LIM domain; Metal-binding; Reference proteome; Repeat; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0005938; C:cell cortex; IEA:Compara.
 GO:0008270; F:zinc ion binding; TAS:ProtInc.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara. 

Interpro

 IPR001781; Znf_LIM. 

Pfam

 PF00412; LIM 

SMART

 SM00132; LIM 

PROSITE

 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 

PRINTS