UniProt Accession

 B8ZZA3_HUMAN; B8ZZA3 

Genbank Protein ID

 AC013437; AC013444 

Genbank Nucleotide ID

  

Protein Name

 Kynureninase 

Protein Synonyms/Alias

  

Gene Name

 KYNU 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
84	GLQPKMVKTYLEEEL	ubiquitination	[1]
93	YLEEELDKWAKIAAY	ubiquitination	[1]
96	EELDKWAKIAAYGHE	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 148 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0030429; F:kynureninase activity; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
 GO:0006569; P:tryptophan catabolic process; IEA:InterPro. 

Interpro

 IPR010111; Kynureninase. 

Pfam

  

SMART

  

PROSITE

  

PRINTS