CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001843
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Xylose isomerase 
Protein Synonyms/Alias
 D-xylulose keto-isomerase 
Gene Name
 xylA 
Gene Synonyms/Alias
 b3565; JW3537 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
341GGLNFDAKVRRQSTDacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 ACT_SITE 101 101
 ACT_SITE 104 104 By similarity.
 METAL 232 232 Magnesium 1 (By similarity).
 METAL 268 268 Magnesium 1 (By similarity).
 METAL 268 268 Magnesium 2 (By similarity).
 METAL 271 271 Magnesium 2 (By similarity).
 METAL 296 296 Magnesium 1 (By similarity).
 METAL 307 307 Magnesium 2 (By similarity).
 METAL 309 309 Magnesium 2 (By similarity).
 METAL 339 339 Magnesium 1 (By similarity).  
Keyword
 Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase; Magnesium; Metal-binding; Pentose shunt; Reference proteome; Xylose metabolism. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MQAYFDQLDR VRYEGSKSSN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH TFCWNGADMF 60
GVGAFNRPWQ QPGEALALAK RKADVAFEFF HKLHVPFYCF HDVDVSPEGA SLKEYINNFA 120
QMVDVLAGKQ EESGVKLLWG TANCFTNPRY GAGAATNPDP EVFSWAATQV VTAMEATHKL 180
GGENYVLWGG REGYETLLNT DLRQEREQLG RFMQMVVEHK HKIGFQGTLL IEPKPQEPTK 240
HQYDYDAATV YGFLKQFGLE KEIKLNIEAN HATLAGHSFH HEIATAIALG LFGSVDANRG 300
DAQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY DLFYGHIGAM 360
DTMALALKIA ARMIEDGELD KRIAQRYSGW NSELGQQILK GQMSLADLAK YAQEHHLSPV 420
HQSGRQEQLE NLVNHYLFDK 440 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0009045; F:xylose isomerase activity; IDA:EcoCyc.
 GO:0042843; P:D-xylose catabolic process; IMP:EcoCyc.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 
Interpro
 IPR013022; Xyl_isomerase-like_TIM-brl.
 IPR013452; Xylose_isom_bac.
 IPR001998; Xylose_isomerase. 
Pfam
 PF01261; AP_endonuc_2 
SMART
  
PROSITE
 PS51415; XYLOSE_ISOMERASE 
PRINTS
 PR00688; XYLOSISMRASE.