UniProt Accession

 HIRP3_HUMAN; Q9BW71; H3BSR3; O75707; O75708 

Genbank Protein ID

 AJ223349; AJ223350; AJ223351; BX393533; AC093512; BC000588 

Genbank Nucleotide ID

 CAA11273.1; CAA11274.1; CAA11275.2; AAH00588.1 

Protein Name

 HIRA-interacting protein 3 

Protein Synonyms/Alias

  

Gene Name

 HIRIP3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
5	***MAREKEMQEFTR	ubiquitination	[1]
47	SHLEPEEKQALKRLV	ubiquitination	[1, 2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones. 

Sequence Annotation

 MOD_RES 27 27 Phosphoserine.
 MOD_RES 84 84 Phosphothreonine.
 MOD_RES 87 87 Phosphoserine.
 MOD_RES 98 98 Phosphoserine.
 MOD_RES 100 100 Phosphoserine.
 MOD_RES 125 125 Phosphoserine.
 MOD_RES 142 142 Phosphoserine.
 MOD_RES 143 143 Phosphoserine.
 MOD_RES 159 159 Phosphoserine.
 MOD_RES 160 160 Phosphoserine.
 MOD_RES 196 196 Phosphoserine.
 MOD_RES 199 199 Phosphoserine.
 MOD_RES 223 223 Phosphoserine.
 MOD_RES 227 227 Phosphoserine.
 MOD_RES 289 289 Phosphoserine.
 MOD_RES 291 291 Phosphoserine.
 MOD_RES 330 330 Phosphoserine.
 MOD_RES 332 332 Phosphoserine.
 MOD_RES 333 333 Phosphoserine.
 MOD_RES 357 357 Phosphoserine.
 MOD_RES 358 358 Phosphothreonine.
 MOD_RES 359 359 Phosphoserine.
 MOD_RES 363 363 Phosphoserine.
 MOD_RES 370 370 Phosphoserine.
 MOD_RES 372 372 Phosphoserine.
 MOD_RES 550 550 Phosphoserine.
 MOD_RES 551 551 Phosphoserine.
 MOD_RES 555 555 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 556 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0006333; P:chromatin assembly or disassembly; TAS:ProtInc. 

Interpro

 IPR019098; Histone_chaperone_domain_CHZ. 

Pfam

 PF09649; CHZ 

SMART

 SM01082; CHZ 

PROSITE

  

PRINTS