CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019136
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G-protein coupled receptor-associated sorting protein 2 
Protein Synonyms/Alias
 GASP-2 
Gene Name
 GPRASP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
39VPLVVRPKVRTQATTubiquitination[1, 2]
618PFIHEISKIAMGMRSubiquitination[3]
792QNISNIIKSGKMSLIubiquitination[3]
820REFEELAKQLQAQIDubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 May play a role in regulation of a variety of G-protein coupled receptors. 
Sequence Annotation
  
Keyword
 Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 838 AA 
Protein Sequence
MTGAEIEPSA QAKPEKKAGE EVIAGPEREN DVPLVVRPKV RTQATTGARP KTETKSVPAA 60
RPKTEAQAMS GARPKTEVQV MGGARPKTEA QGITGARPKT DARAVGGARS KTDAKAIPGA 120
RPKDEAQAWA QSEFGTEAVS QAEGVSQTNA VAWPLATAES GSVTKSKGLS MDRELVNVDA 180
ETFPGTQGQK GIQPWFGPGE ETNMGSWCYS RPRAREEASN ESGFWSADET STASSFWTGE 240
ETSVRSWPRE ESNTRSRHRA KHQTNPRSRP RSKQEAYVDS WSGSEDEASN PFSFWVGENT 300
NNLFRPRVRE EANIRSKLRT NREDCFESES EDEFYKQSWV LPGEEANSRF RHRDKEDPNT 360
ALKLRAQKDV DSDRVKQEPR FEEEVIIGSW FWAEKEASLE GGASAICESE PGTEEGAIGG 420
SAYWAEEKSS LGAVAREEAK PESEEEAIFG SWFWDRDEAC FDLNPCPVYK VSDRFRDAAE 480
ELNASSRPQT WDEVTVEFKP GLFHGVGFRS TSPFGIPEEA SEMLEAKPKN LELSPEGEEQ 540
ESLLQPDQPS PEFTFQYDPS YRSVREIREH LRARESAESE SWSCSCIQCE LKIGSEEFEE 600
FLLLMDKIRD PFIHEISKIA MGMRSASQFT RDFIRDSGVV SLIETLLNYP SSRVRTSFLE 660
NMIHMAPPYP NLNMIETFIC QVCEETLAHS VDSLEQLTGI RMLRHLTMTI DYHTLIANYM 720
SGFLSLLTTA NARTKFHVLK MLLNLSENPA VAKKLFSAKA LSIFVGLFNI EETNDNIQIV 780
IKMFQNISNI IKSGKMSLID DDFSLEPLIS AFREFEELAK QLQAQIDNQN DPEVGQQS 838 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:LIFEdb.
 GO:0001540; F:beta-amyloid binding; IEA:Compara. 
Interpro
 IPR011989; ARM-like.
 IPR006911; ARM-rpt_dom.
 IPR016024; ARM-type_fold. 
Pfam
 PF04826; Arm_2 
SMART
  
PROSITE
  
PRINTS