CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014175
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Anamorsin 
Protein Synonyms/Alias
 Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog 
Gene Name
 Ciapin1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
185HKKSSSVKPVVDPATacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). 
Sequence Annotation
 MOD_RES 182 182 Phosphoserine (By similarity).
 MOD_RES 183 183 Phosphoserine (By similarity).
 MOD_RES 302 302 Phosphoserine (By similarity).
 MOD_RES 304 304 Phosphoserine (By similarity).  
Keyword
 Apoptosis; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
MAEFGISPGQ LVAVFCDKSS SEEALKKLVG RVQGLTGSEG QVFVENITQL LQSAHKESSF 60
DVILSGIVPG STSLHSPEAL ADMARILRPG GCLFLKEPVE TTGVNNDKIK TASKLCSALT 120
LSGLVEIKEL QREALSPEEA QSMQEHLGYH SDSLLSVHVT GKKPNFEVGS SSQLKLLHKK 180
SSSVKPVVDP ATAKLWTLSA NDMEDDSMDL IDSDELLDPE DLKKPDPASL KAPSCGEGKK 240
RKACKNCTCG LAEELEKEQS KAQSSQPKSA CGNCYLGDAF RCANCPYLGM PAFKPGEQVL 300
LSSSNLQDA 309 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0016226; P:iron-sulfur cluster assembly; IEA:HAMAP.
 GO:0043066; P:negative regulation of apoptotic process; IEA:HAMAP. 
Interpro
 IPR007785; Anamorsin. 
Pfam
 PF05093; CIAPIN1 
SMART
  
PROSITE
  
PRINTS