| Tag | Content |
|---|
| CPLM ID | CPLM-024752 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Palmitoyltransferase ZDHHC5 |
Protein Synonyms/Alias | Zinc finger DHHC domain-containing protein 5; DHHC-5 |
Gene Name | ZDHHC5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Bos taurus (Bovine) |
NCBI Taxa ID | 9913 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 224 | TNEQVTGKFRGGVNP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5 and FLOT2 (By similarity). |
Sequence Annotation | ZN_FING 104 154 DHHC-type.
ACT_SITE 134 134 S-palmitoyl cysteine intermediate (By
MOD_RES 91 91 Phosphotyrosine (By similarity).
MOD_RES 247 247 Phosphoserine (By similarity).
MOD_RES 296 296 Phosphoserine (By similarity).
MOD_RES 299 299 Phosphoserine (By similarity).
MOD_RES 345 345 Phosphoserine (By similarity).
MOD_RES 348 348 Phosphothreonine (By similarity).
MOD_RES 380 380 Phosphoserine (By similarity).
MOD_RES 409 409 Phosphoserine (By similarity).
MOD_RES 432 432 Phosphoserine (By similarity).
MOD_RES 436 436 Phosphothreonine (By similarity).
MOD_RES 529 529 Phosphoserine (By similarity).
MOD_RES 554 554 Phosphoserine (By similarity).
MOD_RES 620 620 Phosphoserine (By similarity).
MOD_RES 658 658 Phosphothreonine (By similarity).
MOD_RES 693 693 Phosphoserine (By similarity). |
Keyword | Acyltransferase; Cell membrane; Complete proteome; Membrane; Metal-binding; Phosphoprotein; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 714 AA |
Protein Sequence | MPAESAKRFK PSKYVPVSAA AIFLVGATTL FFAFTCPGLS LSVSPAVPVY NAVVFLFVLA 60
NFSMATFMDP GVFPRAEEDE DKEDDFRAPL YKTVEIKGIQ VRMKWCATCR FYRPPRCSHC 120
SVCDNCVEEF DHHCPWVNNC IGRRNYRYFF LFLLSLTAHI TGVFGFGLLY VLYHMEELSG 180
VRTAVTMAVM CVAGLFFIPV AGLTGFHVVL VARGRTTNEQ VTGKFRGGVN PFTNGCCNNV 240
SRVLCSSPAP RYLGRPKKEK TIVIRPPFLR PEVSDGQITV KIMDNGIQGE LRRTKSKGSL 300
EVTESQSADA EPPPPPKPDL SRYTGLRTHL SLATNEESSL LGKDSPPTPT MYKYRPGYSS 360
SSASAAMPHS SSAKLSRGDS LKEPPSIAES SRQPSYRSEP SLEPESFRSP TLGKGFPFDP 420
LSSGSRSSSL KSAQGTGFEL GPLQSIRSEG TTSTSYKSLA NQTRNGSLSY DSLLTPSDSP 480
DFESVQAGPE PEPPLGYTSP FLSARLAQQR EAERHPRLAP GGPAPREPSP VRYDNLSRHI 540
VASLQEREKL LRQSPPPGRE EEPGLGDSGV QCTPGSGHAP RTSSSSDDSK RSPLGKTPLA 600
RPVAPRFGKP DGLRGRGLAS PEPGLPAPYL GRSVSYSSQK APPGVPETEE VALQPLLTPK 660
DEVQLKTAYS KSNGQPKSIG SAPPGPGQPP LSSPTRGGVK KVSGVGGTTY EISV 714 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0016409; F:palmitoyltransferase activity; IEA:Compara. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0018345; P:protein palmitoylation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |