CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable C-mannosyltransferase DPY19L4 
Protein Synonyms/Alias
 Dpy-19-like protein 4; Protein dpy-19 homolog 4 
Gene Name
 DPY19L4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
104AIYYSYYKDMLKAPSubiquitination[1]
108SYYKDMLKAPSFERGubiquitination[1]
450RINGKSLKETVTLEDubiquitination[1]
623NIYQIYSKRSAEDIYubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 
Functional Description
 Probable C-mannosyltransferase that mediates C- mannosylation of tryptophan residues on target proteins (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Glycosyltransferase; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 723 AA 
Protein Sequence
MAEEEGPPVE LRQRKKPKSS ENKESAKEEK ISDIPIPERA PKHVLFQRFA KIFIGCLAAV 60
TSGMMYALYL SAYHERKFWF SNRQELEREI TFQGDSAIYY SYYKDMLKAP SFERGVYELT 120
HNNKTVSLKT INAVQQMSLY PELIASILYQ ATGSNEIIEP VYFYIGIVFG LQGIYVTALF 180
VTSWLMSGTW LAGMLTVAWF VINRVDTTRI EYSIPLRENW ALPYFACQIA ALTGYLKSNL 240
NTYGERFCYL LMSASTYTFM MMWEYSHYLL FLQAISLFLL DTFSVEQSDK VYEVYKIYIF 300
SLFLGYLLQF ENPALLVSPL LSLVAALMLA KCLQLNVKKG SFVAKIIKVI NFYLVCTLTI 360
TLNIIMKMFV PHKENGHMLK FLEVKFGLNM TKNFTMNWLL CQESLQAPSQ DFFLRLTQSS 420
LLPFYILVLI ICFLSMLQVI FRRINGKSLK ETVTLEDGRI GERPEIIYHV IHTILLGSLA 480
MVIEGLKYIW IPYVCMLAAF GVCSPELWMT LFKWLRLRTV HPILLALILS MAVPTIIGLS 540
LWKEFFPRLM TELMELQEFY DPDTVELMTW IKRQAPVAAV FAGSPQLMGA IKLCTGWMVT 600
SLPLYNDDDL LKRNENIYQI YSKRSAEDIY KILTSYKANY LIVEDAICNE VGPMRGCRVK 660
DLLDIANGHM VCEEGDKLTY SKYGRFCHEV KINYSPYVNY FTRVYWNRSY FVYKINTVIS 720
FQS 723 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW. 
Interpro
 IPR018732; Dpy-19. 
Pfam
 PF10034; Dpy19 
SMART
  
PROSITE
  
PRINTS