UniProt Accession

 HOLE_ECOLI; P0ABS8; P28689 

Genbank Protein ID

 L04572; L05381; U00096; AP009048 

Genbank Nucleotide ID

 AAA23697.1; AAA23982.1; AAC74912.1; BAA15650.1 

Protein Name

 DNA polymerase III subunit theta 

Protein Synonyms/Alias

  

Gene Name

 holE 

Gene Synonyms/Alias

 b1842; JW1831 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
7	*MLKNLAKLDQTEMD	acetylation	[1]
15	LDQTEMDKVNVDLAA	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 76 AA 

Protein Sequence

Gene Ontology

 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
 GO:0006260; P:DNA replication; IEA:UniProtKB-KW. 

Interpro

 IPR009052; DNA_pol_III_theta_bac.
 IPR011325; DNA_pol_III_theta_core_bac. 

Pfam

 PF06440; DNA_pol3_theta 

SMART

  

PROSITE

  

PRINTS