UniProt Accession

 C9JZR4_HUMAN; C9JZR4 

Genbank Protein ID

 AL049757; AL049758 

Genbank Nucleotide ID

  

Protein Name

 ADP-ribosylation factor GTPase-activating protein 3 

Protein Synonyms/Alias

  

Gene Name

 ARFGAP3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
151	KKPNQAKKGLGAKKG	acetylation	[1]
156	AKKGLGAKKGSLGAQ	acetylation	[1]
157	KKGLGAKKGSLGAQK	acetylation	[1]
264	QESPIMAKPRKKYND	ubiquitination	[2]
309	SSDSYWKKETSKDTE	ubiquitination	[2]
320	KDTETVLKTTGYSDR	ubiquitination	[3]
353	QKKFGNVKAISSDMY	ubiquitination	[2]
395	DLFEEPRKQPAGNYS	ubiquitination	[2]

Reference

 [1] Monoclonal antibody cocktail as an enrichment tool for acetylome analysis.
 Shaw PG, Chaerkady R, Zhang Z, Davidson NE, Pandey A.
 Anal Chem. 2011 May 15;83(10):3623-6. [PMID: 21466224]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 444 AA 

Protein Sequence

Gene Ontology

 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 

Interpro

 IPR001164; ArfGAP. 

Pfam

 PF01412; ArfGap 

SMART

 SM00105; ArfGap 

PROSITE

 PS50115; ARFGAP 

PRINTS

 PR00405; REVINTRACTNG.