CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033844
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A 
Protein Synonyms/Alias
  
Gene Name
 Pde9a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
88AFKINELKAEVANHLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
MGAGSSSYRP KAIYLDIDGR IQKVVFSKYC NSSDIMDLFC IATGLPRTPY KVRPVAVKQV 60
SEREELIQGV LAQVAEQFSR AFKINELKAE VANHLAVLEK RVELEGLKVV EIEKCKSDIK 120
KMREELAARN SRTNCPCKYS FLDNKKLTPR RDVPTYPKYL LSPETIEALR KPTFDVWLWE 180
PNEMLSCLEH MYHDLGLVRD FSINPITLRR WLLCVHDNYR NNPFHNFRHC FCVTQMMYSM 240
VWLCGLQEKF SQMDILVLMT AAICHDLDHP GYNNTYQINA RTELAVRYND ISPLENHHCA 300
IAFQILARPE CNIFASVPPE GFRQIRQGMI TLILATDMAR HAEIMDSFKE KMENFDYSNE 360
EHLTLLKMIL IKCCDISNEV RPMEVAEPWV DCLLEEYFMQ SDREKSEGLP VAPFMDRDKV 420
TKATAQIGFI KFVLIPMFET VTKLFPVVEE TMLRPLWESR EHYEELKQLD DAMKELQKKT 480
ESLTSGAPEN TTEKNRDAKD SEGHSPPN 508 
Gene Ontology
 GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR003607; HD/PDEase_dom.
 IPR023088; PDEase.
 IPR002073; PDEase_catalytic_dom.
 IPR023174; PDEase_CS. 
Pfam
 PF00233; PDEase_I 
SMART
 SM00471; HDc 
PROSITE
 PS00126; PDEASE_I 
PRINTS
 PR00387; PDIESTERASE1.