UniProt Accession

 EF1G2_YEAST; P36008; D6VXK6 

Genbank Protein ID

 L01880; Z28081; Z28080; M77143; BK006944 

Genbank Nucleotide ID

 AAA21473.1; CAA81919.1; CAA81918.1; DAA09076.1 

Protein Name

 Elongation factor 1-gamma 2 

Protein Synonyms/Alias

 EF-1-gamma 2; Eukaryotic elongation factor 1Bgamma 2; eEF1Bgamma 2; Translation elongation factor 1B gamma 2 

Gene Name

 TEF4 

Gene Synonyms/Alias

 EFC1; YKL081W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
46	FASLFPLKQAPAFLG	ubiquitination	[1]
77	ANQVADEKERARLLG	ubiquitination	[2]
90	LGSDVIEKSQILRWA	acetylation	[3]
90	LGSDVIEKSQILRWA	ubiquitination	[2]
116	ARPFLSFKGLIPYNK	acetylation	[3]
123	KGLIPYNKKDVDACF	acetylation	[3]
124	GLIPYNKKDVDACFV	acetylation	[3]
199	VAASPIVKTPFAEVK	ubiquitination	[2]
206	KTPFAEVKLAEKALT	acetylation	[3]
210	AEVKLAEKALTYTPP	acetylation	[3]
210	AEVKLAEKALTYTPP	ubiquitination	[2]
240	EKKKDEAKPADDAAP	ubiquitination	[1]
379	YTKLDPTKEEDKEFV	acetylation	[3]
394	NNMWAWDKPVVVNGE	acetylation	[3]

Reference

 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Subunit of the eukaryotic elongation factor 1 complex (eEF1). Probably plays a role in anchoring the complex to other cellular components (By similarity). 

Sequence Annotation

 DOMAIN 1 77 GST N-terminal.
 DOMAIN 86 217 GST C-terminal.
 DOMAIN 251 412 EF-1-gamma C-terminal.  

Keyword

 Complete proteome; Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 412 AA 

Protein Sequence

Gene Ontology

 GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005840; C:ribosome; TAS:SGD.
 GO:0003746; F:translation elongation factor activity; TAS:SGD. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR012336; Thioredoxin-like_fold.
 IPR001662; Transl_elong_EF1_G_con. 

Pfam

 PF00647; EF1G
 PF00043; GST_C
 PF02798; GST_N 

SMART

  

PROSITE

 PS50040; EF1G_C
 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS