CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028320
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-isopropylmalate dehydratase small subunit 
Protein Synonyms/Alias
 Alpha-IPM isomerase; Isopropylmalate isomerase 
Gene Name
 leuD 
Gene Synonyms/Alias
 MSMEG_2388; MSMEI_2328 
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
61LNLSPFDKGSVLVAGpupylation[1]
Reference
 [1] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680
Functional Description
 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity). 
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Leucine biosynthesis; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 197 AA 
Protein Sequence
MEAFTTHTGI GVPLRRSNVD TDQIIPAVYL KRVTRTGFED GLFAAWRNDP SFILNLSPFD 60
KGSVLVAGPD FGTGSSREHA VWALMDYGFR VVISSRFADI FRGNAGKAGL LAAEVAQDDV 120
ELLWKVIEQN PGLEITVNLQ DRTVTAGTVV VPFRIDDYTR WRLLEGLDDI GLTLRKLDQI 180
EAYEAARPAW KPRTLPA 197 
Gene Ontology
 GO:0009316; C:3-isopropylmalate dehydratase complex; IEA:InterPro.
 GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:HAMAP.
 GO:0009098; P:leucine biosynthetic process; IEA:HAMAP. 
Interpro
 IPR004431; 3-IsopropMal_deHydase_ssu.
 IPR015937; Acoase/IPM_deHydtase.
 IPR015928; Aconitase/3IPM_dehydase_swvl.
 IPR000573; AconitaseA/IPMdHydase_ssu_swvl. 
Pfam
 PF00694; Aconitase_C 
SMART
  
PROSITE
  
PRINTS