| Tag | Content |
|---|
| CPLM ID | CPLM-043027 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | RAS guanyl-releasing protein 1 |
Protein Synonyms/Alias | |
Gene Name | RASGRP1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 361 | HSSISRLKETSSHVP | ubiquitination | [1] | | 373 | HVPHEINKVLGEMTE | ubiquitination | [1] | | 498 | APPLTPSKPPVVVDW | ubiquitination | [1] | | 531 | RMVDSVFKNYDHDQD | ubiquitination | [1] | | 562 | FSFCVMDKDREGLIS | ubiquitination | [1] | | 635 | MNCHKQCKDLVVFEC | ubiquitination | [1] | | 644 | LVVFECKKRAKNPVA | ubiquitination | [1] | | 647 | FECKKRAKNPVAPTE | ubiquitination | [1] | | 748 | FVLSSPRKTAQDTLY | ubiquitination | [1] | | 781 | AFVKWENKDSLIKSK | ubiquitination | [1] | | 826 | QLKYAQKKIESLQLE | ubiquitination | [1] | | 834 | IESLQLEKSNHVLAQ | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | Calcium; Complete proteome; Guanine-nucleotide releasing factor; Metal-binding; Reference proteome; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 848 AA |
Protein Sequence | MKVVPTSPTP TDARRPRLGQ IWITPVERTS TQAALVQGAG RRAQGTCLRP SPADGYLETP 60
GHRKPSHGCR AASKARLEAK PANSPFPSHP SLAHITQFRM MVSLGHLAKG ASLDDLIDSC 120
IQSFDADGNL CRSNQLLQVM LTMHRIVISS AELLQKVITL YKDALAKNSP GLCLKICYFV 180
RYWITEFWVM FKMDASLTDT MEEFQELVKA KGEELHCRLI DTTQINARDW SRKLTQRIKS 240
NTSKKRKVSL LFDHLEPEEL SEHLTYLEFK SFRRISFSDY QNYLVNSCVK ENPTMERSIA 300
LCNGISQWVQ LMVLSRPTPQ LRAEVFIKFI QVAQKLHQLQ NFNTLMAVIG GLCHSSISRL 360
KETSSHVPHE INKVLGEMTE LLSSSRNYDN YRRAYGECTD FKIPILGVHL KDLISLYEAM 420
PDYLEDGKVN VHKLLALYNH ISELVQLQEV APPLEANKDL VHLLTLSLDL YYTEDEIYEL 480
SYAREPRNHR APPLTPSKPP VVVDWASGVS PKPDPKTISK HVQRMVDSVF KNYDHDQDGY 540
ISQEEFEKIA ASFPFSFCVM DKDREGLISR DEITAYFMRA SSIYSKLGLG FPHNFQETTY 600
LKPTFCDNCA GFLWGVIKQG YRCKDCGMNC HKQCKDLVVF ECKKRAKNPV APTENNTSVG 660
PVSNLCSLGA KDLLHAPEEG PFTFPNGEAV EHGEESKDRT IMLMGVSSQK ISLRLKRAVA 720
HKATQTESQP WIGSEGPSGP FVLSSPRKTA QDTLYVLPSP TSPCPSPVLV RKRAFVKWEN 780
KDSLIKSKEE LRHLRLPTYQ ELEQEINTLK ADNDALKIQL KYAQKKIESL QLEKSNHVLA 840
QMEQGDCS 848 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |