CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022696
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pleckstrin homology domain-containing family B member 2 
Protein Synonyms/Alias
 PH domain-containing family B member 2; Evectin-2 
Gene Name
 Plekhb2 
Gene Synonyms/Alias
 Evt2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
46TRQSIEDKVHMPVDCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Involved in retrograde transport of recycling endosomes (By similarity). 
Sequence Annotation
 DOMAIN 2 109 PH.
 BINDING 20 20 Phosphatidylserine (By similarity).  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Endosome; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 221 AA 
Protein Sequence
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QSIEDKVHMP VDCINIRTGH 60
ECRDIQPPDG KPRDCLLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAILS 120
EETAVAASPP PYAAYATPTP EVYGYGPYSG AYPAGTQVVY AANGQAYAVP YQYPYAGVYG 180
QQPANQVIIR ERYRDNDSDL ALGMLAGAAT GMALGSLFWV F 221 
Gene Ontology
 GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005543; F:phospholipid binding; IEA:InterPro. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF00169; PH 
SMART
 SM00233; PH 
PROSITE
 PS50003; PH_DOMAIN 
PRINTS