CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014676
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Catenin alpha-3 
Protein Synonyms/Alias
 Alpha T-catenin; Cadherin-associated protein 
Gene Name
 Ctnna3 
Gene Synonyms/Alias
 Catna3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
190SLDYLAFKRQQDLKSubiquitination[1]
352EYMSNTGKTERSNTLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May be involved in formation of stretch-resistant cell- cell adhesion complexes (By similarity). 
Sequence Annotation
 MOD_RES 637 637 Phosphoserine.  
Keyword
 Cell adhesion; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 895 AA 
Protein Sequence
MSAETPITLN MDTQDLQIQT FTVEKLLEPL IIQVTTLVNC PQNPSNRKKG RSKRARVLLA 60
SVEEATWNLL DKGEMIAKEA TVLKEELAAA LQEVRKESKA LKVSAERFTD DPCYLPKREA 120
VVQAARALLA AVTRLLVLAD MIDVMCLLQH VSSFQRTFES LKNVSNKSDL QRTYQKLGKE 180
LESLDYLAFK RQQDLKSPSQ RDEIAGARAT LKENSPLLHS ICSACLEHSD VASLKASKDT 240
VCEEIQNALD VISNASQGIQ NAPAPPEPQA ATLGSAFDEL ENLIVLNPLT VTEEDVRPSL 300
EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLTEYMSNT GKTERSNTLN 360
TAIVNMSKKT RDLRRQLRKA IIDHISDSFL DTTVPLLVLI EAAKNGRVKE IKDYAAIFHE 420
HTGRLVEVAN LACSMSTNED GIKIVRIAAN HLETLCPQII NAALALASRP KSQVVKNTME 480
MYKRTWEHYI HVLTEAVDDI TSIDDFLAVS ESHILEDVNK CIIALRDQDA DNLDRAAGAI 540
RGRAARVAHI VAGEMDSYEP GAYTEGVMRN VNFLTSTVIP EFVTQVNVAL DALSKNSLTA 600
LDDNQFVDIS KKIYDTIHDI RCSVMMIRTP EELEDVSDLE DDHEVRSHTS IQTEGKTDRA 660
KMTQLPEAEK EKIAEQVADF KKVKSKLDAE IEIWDDTSND IIVLAKKMCM IMMEMTDFTR 720
GKGPLKHTTD VIYAAKMISE SGSRMDVLAR QIANQCPDPP CKQDLLAYLE QIKFYSHQLK 780
ICSQVKAEIQ NLGGELIVSA LDSVTSLIQA AKNLMNAVVQ TVKMSYIAST KIIRIQSSAG 840
PRHPVVMWRM KAPAKKPLIK REKPEETWAA VRRGSAKKKI HPVQVMSEFR GRQVY 895 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:InterPro.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005916; C:fascia adherens; ISS:UniProtKB.
 GO:0030027; C:lamellipodium; IDA:MGI.
 GO:0045296; F:cadherin binding; TAS:UniProtKB.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0016337; P:cell-cell adhesion; IDA:UniProtKB. 
Interpro
 IPR001033; Alpha_catenin.
 IPR006077; Vinculin/catenin. 
Pfam
 PF01044; Vinculin 
SMART
  
PROSITE
 PS00663; VINCULIN_1 
PRINTS
 PR00805; ALPHACATENIN.