CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031071
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cellular nucleic acid-binding protein 
Protein Synonyms/Alias
 cDNA FLJ61146, highly similar to Cellular nucleic acid-binding protein 
Gene Name
 CNBP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MSSNECFKCGRSGHWacetylation[1]
8MSSNECFKCGRSGHWubiquitination[1, 2, 3]
48GESGHLAKDCDLQEDacetylation[1]
48GESGHLAKDCDLQEDubiquitination[3]
68GRGGHIAKDCKEPKRacetylation[1]
86QCCYNCGKPGHLARDacetylation[1]
86QCCYNCGKPGHLARDubiquitination[1, 3]
101CDHADEQKCYSCGEFubiquitination[1, 3]
113GEFGHIQKDCTKVKCubiquitination[1, 3]
117HIQKDCTKVKCYRCGubiquitination[1]
135HVAINCSKTSEVNCYubiquitination[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MSSNECFKCG RSGHWARECP TGGGRGRGMR SRGRDICYRC GESGHLAKDC DLQEDACYNC 60
GRGGHIAKDC KEPKREREQC CYNCGKPGHL ARDCDHADEQ KCYSCGEFGH IQKDCTKVKC 120
YRCGETGHVA INCSKTSEVN CYRCGESGHL ARECTIEATA 160 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001878; Znf_CCHC. 
Pfam
 PF00098; zf-CCHC 
SMART
 SM00343; ZnF_C2HC 
PROSITE
 PS50158; ZF_CCHC 
PRINTS