CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027100
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TBC1 domain family, member 15 
Protein Synonyms/Alias
  
Gene Name
 Tbc1d15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
26YIHSSCGKANDQDSLubiquitination[1]
322LVAVESMKQKIFRGGubiquitination[1]
352YFPWDSTKEERTQLQubiquitination[1]
396DYRSLIEKDVNRTDRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 671 AA 
Protein Sequence
MAAAGVVSGK IIYEQEGVYI HSSCGKANDQ DSLISGILRV LEKDAEVIVD WRPLDDALDS 60
SSILCAGKDS SSVVEWTQAP KERAHRGSDQ QSSYEAEWDM VTTVSFKKKP HTNGDAPGHR 120
NGKSKWSFLF SLADLKSVKQ SKEGMGWSYL VFCLKDDVML PALHFHQGDS KLLIESLEKY 180
VVLCESPQDS RTLLVNCQNK SLSQSFENLL DEPAYGLTQK IKKDPYTATM VGFSKVTNYI 240
FDSLRGSDPS THQRPPSEMA DFLSDAIPGL KINQQEEPGF EVITRIDLGE RPVVQRREPV 300
SLEEWNKSLD PEGRLVAVES MKQKIFRGGL SHSLRKQAWK FLLGYFPWDS TKEERTQLQK 360
QKTDEYFRMK LQWKSVSEAQ EKRNSRLRDY RSLIEKDVNR TDRTNKFYEG QDNPGLILLH 420
DILMTYCMYD FDLGYVQGMS DLLSPLLYVM ENEVDAFWCF ASYMDQMHQN FEEQMQGMKT 480
QLIQLSTLLR LLDSGFCSYL ESQDSGYLYF CFRWLLIRFK REFSFLDILR LWEVMWTELP 540
CKNFHLLLCC AILESEKQQI MAKHYGFNEI LKHINELSMK IDVEDILCKA EAISLQMAQC 600
KELPQAVCEI LGLQDNEITT PDSDTDENVG SPCPVSAFPS STLPILAASE AKDDSPTQTL 660
ASPNACRLTP A 671 
Gene Ontology
 GO:0005576; C:extracellular region; IDA:MGI.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
 GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. 
Interpro
 IPR021935; DUF3548.
 IPR000195; Rab-GTPase-TBC_dom. 
Pfam
 PF12068; DUF3548
 PF00566; RabGAP-TBC 
SMART
 SM00164; TBC 
PROSITE
 PS50086; TBC_RABGAP 
PRINTS