UniProt Accession

 EIF3J_YEAST; Q05775; D6VYJ5 

Genbank Protein ID

 U14913; AY557943; BK006945 

Genbank Nucleotide ID

 AAB67433.1; AAS56269.1; DAA09511.1 

Protein Name

 Eukaryotic translation initiation factor 3 subunit J 

Protein Synonyms/Alias

 eIF3j; Eukaryotic translation initiation factor 3 30 kDa subunit; eIF-3 30 kDa 

Gene Name

 HCR1 

Gene Synonyms/Alias

 YLR192C; L8167.11 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
118	PRARALQKEQEEQAL	ubiquitination	[1]
126	EQEEQALKRPAFTKD	acetylation	[2]
132	LKRPAFTKDTPIETH	acetylation	[2]
147	PLFNAETKREYQDLR	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Probable component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. 

Sequence Annotation

 MOD_RES 75 75 Phosphothreonine.
 MOD_RES 92 92 Phosphoserine.  

Keyword

 Complete proteome; Cytoplasm; Initiation factor; Phosphoprotein; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 265 AA 

Protein Sequence

Gene Ontology

 GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP.
 GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP.
 GO:0005852; C:eukaryotic translation initiation factor 3 complex; IPI:SGD.
 GO:0003743; F:translation initiation factor activity; IPI:SGD.
 GO:0002181; P:cytoplasmic translation; IPI:SGD.
 GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP.
 GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0006446; P:regulation of translational initiation; IEA:HAMAP. 

Interpro

 IPR023194; eIF3-like_dom.
 IPR013906; eIF3j. 

Pfam

 PF08597; eIF3_subunit 

SMART

  

PROSITE

  

PRINTS