CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006792
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nitrate/nitrite transporter NarU 
Protein Synonyms/Alias
 Nitrite extrusion protein 2; Nitrite facilitator 2 
Gene Name
 narU 
Gene Synonyms/Alias
 yddF; b1469; JW1464 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
17RYLLRDWKPENPAFWacetylation[1]
27NPAFWENKGKHIARRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Catalyzes nitrate uptake, nitrite uptake and nitrite export across the cytoplasmic membrane. May function as a nitrate/H(+) and nitrite/H(+) channel. Could confer a selective advantage during severe nutrient starvation or slow growth. 
Sequence Annotation
  
Keyword
 3D-structure; Cell inner membrane; Cell membrane; Complete proteome; Membrane; Nitrate assimilation; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MALQNEKNSR YLLRDWKPEN PAFWENKGKH IARRNLWISV SCLLLAFCVW MLFSAVTVNL 60
NKIGFNFTTD QLFLLTALPS VSGALLRVPY SFMVPIFGGR RWTVFSTAIL IIPCVWLGIA 120
VQNPNTPFGI FIVIALLCGF AGANFASSMG NISFFFPKAK QGSALGINGG LGNLGVSVMQ 180
LVAPLVIFVP VFAFLGVNGV PQADGSVMSL ANAAWIWVPL LAIATIAAWS GMNDIASSRA 240
SIADQLPVLQ RLHLWLLSLL YLATFGSFIG FSAGFAMLAK TQFPDVNILR LAFFGPFIGA 300
IARSVGGAIS DKFGGVRVTL INFIFMAIFS ALLFLTLPGT GSGNFIAFYA VFMGLFLTAG 360
LGSGSTFQMI AVIFRQITIY RVKMKGGSDE QAHKEAVTET AAALGFISAI GAVGGFFIPQ 420
AFGMSLNMTG SPVGAMKVFL IFYIVCVLLT WLVYGRRKFS QK 462 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005452; F:inorganic anion exchanger activity; IGI:EcoCyc.
 GO:0015112; F:nitrate transmembrane transporter activity; IGI:EcoCyc.
 GO:0015514; F:nitrite efflux transmembrane transporter activity; IGI:EcoCyc.
 GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW. 
Interpro
 IPR011701; MFS.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR004737; NO3_transporter. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS