CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009799
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinyl-CoA ligase [ADP-forming] subunit beta 
Protein Synonyms/Alias
 Succinyl-CoA synthetase subunit beta; SCS-beta 
Gene Name
 sucC 
Gene Synonyms/Alias
 STM0738 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
56VHAGGRGKAGGVKVVacetylation[1]
61RGKAGGVKVVKSKEEacetylation[1]
64AGGVKVVKSKEEIRAacetylation[1]
66GVKVVKSKEEIRAFAacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 DOMAIN 9 244 ATP-grasp.
 NP_BIND 35 108 ATP (By similarity).
 METAL 197 197 Magnesium or manganese (By similarity).
 METAL 199 199 Magnesium or manganese (By similarity).  
Keyword
 ATP-binding; Complete proteome; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Reference proteome; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 388 AA 
Protein Sequence
MNLHEYQAKQ LFARYGLPAP VGYACTTPRE AEEAASKIGA GPWVVKCQVH AGGRGKAGGV 60
KVVKSKEEIR AFAENWLGKR LVTYQTDANG QPVNQILVEA ATDIGKELYL GAVVDRSSRR 120
VVFMASTEGG VEIEKVAEET PHLIHKVALD PLTGPMPYQG RELAFKLGLE GKLVQQFTKI 180
FMGLATIFLE RDLALIEINP LVITKQGDLI CLDGKLGADG NALFRQPDLR EMRDQSQEDP 240
REAQAAQWEL NYVALDGNIG CMVNGAGLAM GTMDIVKLHG GEPANFLDVG GGATKERVTE 300
AFKIILSDDN VKAVLVNIFG GIVRCDLIAD GIIGAVEEVG VNVPVVVRLE GNNAELGAKK 360
LADSGLNIIA AKSLTDAAQQ VVAAVEGK 388 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0030145; F:manganese ion binding; IEA:HAMAP.
 GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:HAMAP.
 GO:0006099; P:tricarboxylic acid cycle; IEA:HAMAP. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS