CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030873
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 
Protein Synonyms/Alias
 cDNA FLJ57993, highly similar to Mitogen-activated protein kinase kinase kinase7-interacting protein 2 
Gene Name
 TAB2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
612FVGPVPPKPKDQRSIubiquitination[1]
621KDQRSIIKTPKTQDTubiquitination[1, 2]
624RSIIKTPKTQDTEDDubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 661 AA 
Protein Sequence
MQNNNNLDAC CAVLSQESTR YLYGEGDLNF SDDSGISGLR NHMTSLNLDL QSQNIYHHGR 60
EGSRMNGSRT LTHSISDGQL QGGQSNSELF QQEPQTAPAQ VPQGFNVFGM SSSSGASNSA 120
PHLGFHLGSK GTSSLSQQTP RFNPIMVTLA PNIQTGRNTP TSLHIHGVPP PVLNSPQGNS 180
IYIRPYITTP GGTTRQTQQH SGWVSQFNPM NPQQVYQPSQ PGPWTTCPAS NPLSHTSSQQ 240
PNQQGHQTSH VYMPISSPTT SQPPTIHSSG SSQSSAHSQY NIQNISTGPR KNQIEIKLEP 300
PQRNNSSKLR SSGPRTSSTS SSVNSQTLNR NQPTVYIAAS PPNTDELMSR SQPKVYISAN 360
AATGDEQVMR NQPTLFISTN SGASAASRNM SGQVSMGPAF IHHHPPKSRA IGNNSATSPR 420
VVVTQPNTKY TFKITVSPNK PPAVSPGVVS PTFELTNLLN HPDHYVETEN IQHLTDPTLA 480
HVDRISETRK LSMGSDDAAY TQALLVHQKA RMERLQRELE IQKKKLDKLK SEVNEMENNL 540
TRRRLKRSNS ISQIPSLEEM QQLRSCNRQL QIDIDCLTKE IDLFQARGPH FNPSAIHNFY 600
DNIGFVGPVP PKPKDQRSII KTPKTQDTED DEGAQWNCTA CTFLNHPALI RCEQCEMPRH 660
F 661 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001876; Znf_RanBP2. 
Pfam
 PF00641; zf-RanBP 
SMART
 SM00547; ZnF_RBZ 
PROSITE
 PS01358; ZF_RANBP2_1
 PS50199; ZF_RANBP2_2 
PRINTS