CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009197
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chromosome partition protein MukF 
Protein Synonyms/Alias
 Protein KicB 
Gene Name
 mukF 
Gene Synonyms/Alias
 kicB; b0922; JW0905 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
195DIAQLLNKDWRAAISacetylation[1]
228TLEAAGDKLQANLLRacetylation[1]
421DFTGLPAKWQPINDYacetylation[1]
431PINDYGAKVQAHVIDacetylation[1]
439VQAHVIDKY******acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. 
Sequence Annotation
 REGION 208 236 Leucine-zipper.  
Keyword
 3D-structure; Calcium; Cell cycle; Cell division; Chromosome partition; Complete proteome; Cytoplasm; Direct protein sequencing; DNA condensation; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MSEFSQTVPE LVAWARKNDF SISLPVDRLS FLLAVATLNG ERLDGEMSEG ELVDAFRHVS 60
DAFEQTSETI GVRANNAIND MVRQRLLNRF TSEQAEGNAI YRLTPLGIGI TDYYIRQREF 120
STLRLSMQLS IVAGELKRAA DAAEEGGDEF HWHRNVYAPL KYSVAEIFDS IDLTQRLMDE 180
QQQQVKDDIA QLLNKDWRAA ISSCELLLSE TSGTLRELQD TLEAAGDKLQ ANLLRIQDAT 240
MTHDDLHFVD RLVFDLQSKL DRIISWGQQS IDLWIGYDRH VHKFIRTAID MDKNRVFAQR 300
LRQSVQTYFD EPWALTYANA DRLLDMRDEE MALRDEEVTG ELPEDLEYEE FNEIREQLAA 360
IIEEQLAVYK TRQVPLDLGL VVREYLSQYP RARHFDVARI VIDQAVRLGV AQADFTGLPA 420
KWQPINDYGA KVQAHVIDKY 440 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:HAMAP.
 GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
 GO:0005509; F:calcium ion binding; IEA:HAMAP.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IEA:HAMAP.
 GO:0006260; P:DNA replication; IEA:HAMAP. 
Interpro
 IPR005582; Chromosome_partition_MukF.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF03882; KicB 
SMART
  
PROSITE
  
PRINTS