CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026814
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tripartite motif-containing 27 
Protein Synonyms/Alias
  
Gene Name
 Trim27 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
471WEVEVGDKAKWTIGVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 604 AA 
Protein Sequence
TLPGEPARGA RFPTPLGSAL SRAPGPRPPP RAVGEEQLCG DGSGRPRAPR ASAIPAPEAP 60
PRSGAEKRSE RAELRQSSAP GSCPAAQPAR AMASGSVAEC LQQETTCPVC LQYFVEPMML 120
DCGHNICCAC LARCWGAAET NVSCPQCRET FPQRHMRPNR HLANVTQLVK QLRTERPSGP 180
GGEMGVCEKH REPLKLYCEQ DQMPICVVCD RSREHRGHSV LPLEEAVEGF KEQIQNRLDH 240
LRRVKDLKKR RRAQGEQARA ELLSLTQMER EKIVWEFEQL YHSLKEHEYR LLARLEELDL 300
AIYNSINGAI TQFSCNISHL SGLIAQLEEK QQQPTRELLQ DIGDTLSRAE RIRIPEPWIT 360
PPDLQEKIHI FAQKCLFLTE SLKQFTEKMQ SDMEKIQELR EAQLYSVDVT LDPDTAYPSL 420
ILSDNLRQVR YSYLQQDLPD NPERFNLFPC VLGSPCFMAG RHYWEVEVGD KAKWTIGVCE 480
DSVCRKGGVT SAPQNGFWAV SLWYGKEYWA LTSPMTALPL RTPLQRVGIF LDYDAGEVSF 540
YNVTERCHTF TFSHATFCGP VRPYFSLSYS GGKSAAPLII CPMSGIDGFS GHVGNHGHSM 600
ETSP 604 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0031965; C:nuclear membrane; ISO:MGI.
 GO:0005654; C:nucleoplasm; ISO:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0045814; P:negative regulation of gene expression, epigenetic; ISO:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI. 
Interpro
 IPR001870; B30.2/SPRY.
 IPR003879; Butyrophylin.
 IPR008985; ConA-like_lec_gl_sf.
 IPR006574; PRY.
 IPR018355; SPla/RYanodine_receptor_subgr.
 IPR003877; SPRY_rcpt.
 IPR000315; Znf_B-box.
 IPR020457; Znf_B-box_chordata.
 IPR018957; Znf_C3HC4_RING-type.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00622; SPRY
 PF00643; zf-B_box
 PF00097; zf-C3HC4 
SMART
 SM00336; BBOX
 SM00589; PRY
 SM00184; RING
 SM00449; SPRY 
PROSITE
 PS50188; B302_SPRY
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS
 PR01406; BBOXZNFINGER.
 PR01407; BUTYPHLNCDUF.