CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015430
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peptidase inhibitor 16 
Protein Synonyms/Alias
 PI-16; Cysteine-rich secretory protein 9; CRISP-9; PSP94-binding protein 
Gene Name
 PI16 
Gene Synonyms/Alias
 CRISP9; PSPBP; PSEC0164; UNQ289/PRO328 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
174PPGNVKGKRPYQEGTubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Putative serine protease inhibitor (By similarity). 
Sequence Annotation
 DOMAIN 37 165 SCP.
 REGION 386 395 O-glycosylated at one site.
 CARBOHYD 114 114 N-linked (GlcNAc...) (Potential).
 CARBOHYD 403 403 N-linked (GlcNAc...) (Potential).
 CARBOHYD 409 409 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Direct protein sequencing; Glycoprotein; Membrane; Polymorphism; Protease inhibitor; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 463 AA 
Protein Sequence
MHGSCSFLML LLPLLLLLVA TTGPVGALTD EEKRLMVELH NLYRAQVSPT ASDMLHMRWD 60
EELAAFAKAY ARQCVWGHNK ERGRRGENLF AITDEGMDVP LAMEEWHHER EHYNLSAATC 120
SPGQMCGHYT QVVWAKTERI GCGSHFCEKL QGVEETNIEL LVCNYEPPGN VKGKRPYQEG 180
TPCSQCPSGY HCKNSLCEPI GSPEDAQDLP YLVTEAPSFR ATEASDSRKM GTPSSLATGI 240
PAFLVTEVSG SLATKALPAV ETQAPTSLAT KDPPSMATEA PPCVTTEVPS ILAAHSLPSL 300
DEEPVTFPKS THVPIPKSAD KVTDKTKVPS RSPENSLDPK MSLTGARELL PHAQEEAEAE 360
AELPPSSEVL ASVFPAQDKP GELQATLDHT GHTSSKSLPN FPNTSATANA TGGRALALQS 420
SLPGAEGPDK PSVVSGLNSG PGHVWGPLLG LLLLPPLVLA GIF 463 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030414; F:peptidase inhibitor activity; IEA:UniProtKB-KW. 
Interpro
 IPR001283; Allrgn_V5/Tpx1.
 IPR018244; Allrgn_V5/Tpx1_CS.
 IPR014044; CAP_domain. 
Pfam
 PF00188; CAP 
SMART
 SM00198; SCP 
PROSITE
 PS01009; CRISP_1
 PS01010; CRISP_2 
PRINTS
 PR00837; V5TPXLIKE.