CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038006
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol-binding clathrin assembly protein 
Protein Synonyms/Alias
  
Gene Name
 Picalm 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
163MRTMNTEKLLKTVPIacetylation[1]
460DSGGGLLKPTVASQNacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 597 AA 
Protein Sequence
MSGQSLTDRI TAAQHSVTGS AVSKTVCKAT THEIMGPKKK HLDYLIQCTN EMNVNIPQLA 60
DSLFERTTNS SWVVVFKSLI TTHHLMVYGN ERFIQYLASR NTLFNLSNFL DKSGLQGYDM 120
STFIRRYSRY LNEKAVSYRQ VAFDFTKVKR GADGVMRTMN TEKLLKTVPI IQNQMDALLD 180
FNVNSNELTN GVINAAFMLL FKDAIRLFAA YNEGIINLLE KYFDMKKNQC KEGLDIYKKF 240
LTRMTRISEF LKVAEQVGID RGDIPDLSQA PSSLLDALEQ HLASLEGKKI KDSTAASRAT 300
TLSNAVSSLA STGLSLTKVD EREKQAALEE EQARLKALKE QRLKELAKKP HTSLTTAASP 360
VSTSAGGIMT APAIDIFSTP SSSNSTSKLP NDLLDLQQPT FHPSVHAMSA APQVASTWGG 420
FSPSPVTQPH PSAGLNVDFE SVFGNKSTNV AVDSGGGLLK PTVASQNQSL PVAKLAPNKL 480
VSDDLDSSLA NLVGNLGIGN GTTKNDVSWS QPGEKKLTGG SNWQPKVAPT TAWSAATMAP 540
PVMAYPATTP TGMIGYGIPP QMGSVPVMTQ PTLIYSQPVM RPPNPFGPVP GAQIQVL 597 
Gene Ontology
 GO:0030122; C:AP-2 adaptor complex; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
 GO:0007409; P:axonogenesis; IEA:Compara.
 GO:0048268; P:clathrin coat assembly; IEA:InterPro.
 GO:0048813; P:dendrite morphogenesis; IEA:Compara.
 GO:0016197; P:endosomal transport; IEA:Compara.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0048261; P:negative regulation of receptor-mediated endocytosis; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0031623; P:receptor internalization; IEA:Compara.
 GO:0032880; P:regulation of protein localization; IEA:Compara. 
Interpro
 IPR011417; ANTH_dom.
 IPR014712; Clathrin_Pinositid-bd_GAT-like.
 IPR008942; ENTH_VHS.
 IPR013809; Epsin-like_N. 
Pfam
 PF07651; ANTH 
SMART
 SM00273; ENTH 
PROSITE
 PS50942; ENTH 
PRINTS