CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003355
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Right origin-binding protein 
Protein Synonyms/Alias
  
Gene Name
 rob 
Gene Synonyms/Alias
 b4396; JW4359 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
35AAKAGYSKWHLQRMFacetylation[1]
43WHLQRMFKDVTGHAIacetylation[1]
271YYPAEDAKAGDRPINacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication. 
Sequence Annotation
 DNA_BIND 24 43 H-T-H motif (By similarity).  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 289 AA 
Protein Sequence
MDQAGIIRDL LIWLEGHLDQ PLSLDNVAAK AGYSKWHLQR MFKDVTGHAI GAYIRARRLS 60
KSAVALRLTA RPILDIALQY RFDSQQTFTR AFKKQFAQTP ALYRRSPEWS AFGIRPPLRL 120
GEFTMPEHKF VTLEDTPLIG VTQSYSCSLE QISDFRHEMR YQFWHDFLGN APTIPPVLYG 180
LNETRPSQDK DDEQEVFYTT ALAQDQADGY VLTGHPVMLQ GGEYVMFTYE GLGTGVQEFI 240
LTVYGTCMPM LNLTRRKGQD IERYYPAEDA KAGDRPINLR CELLIPIRR 289 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IDA:EcoliWiki.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. 
Interpro
 IPR010499; AraC_E-bd.
 IPR009057; Homeodomain-like.
 IPR018060; HTH_AraC.
 IPR018062; HTH_AraC-typ_CS.
 IPR011256; Reg_factor_effector_bac.
 IPR020449; Tscrpt_reg_HTH_AraC-type. 
Pfam
 PF06445; GyrI-like 
SMART
 SM00871; AraC_E_bind
 SM00342; HTH_ARAC 
PROSITE
 PS00041; HTH_ARAC_FAMILY_1
 PS01124; HTH_ARAC_FAMILY_2 
PRINTS
 PR00032; HTHARAC.