CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026993
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LD15481p 
Protein Synonyms/Alias
 Rs1 
Gene Name
 Rs1 
Gene Synonyms/Alias
 CG2173; Dmel_CG2173 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
227LYRPLNNKAITRVLVacetylation[1]
572KTEQQLSKTERKLLGacetylation[1]
664KTPEQLAKERAMKEIacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Nucleotidyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 782 AA 
Protein Sequence
MGATKNLDLI GTIEDDAEVE NLSEDSDAEV EYQPTKLRHK KVTEFEKGFE FVSSVKEYNQ 60
DTWDDLMKYV KRKARTKTDD KIAARLQKRG GAEAVAAEQS DGSEIDLSED ELKHDNLRLR 120
EKKESKKKKK KAGEEDEEDE GEKMQFADTV EANEQITSFY QMNLSRPLMR AIGVLGYIYP 180
TPIQASTIPV ALLGRDICGC AATGTGKTAA YMLPTLERLL YRPLNNKAIT RVLVLVPTRE 240
LGAQVYQVTK QLCQFTTIDV GLAIGGLDVK AQEAVLRQNP DIVIATPGRL IDHIKNTPSF 300
TLDSIEVLIL DEADRMLDEY FAEQMKEIIN SCCKTRQTML FSATMSEQVK DLAAVSLDKP 360
IKVFVNNNQQ VAFNLRQEFI RIREDKEGDR EPILASLICR TFHDHCMVFV QTKKQAHRLH 420
ILLGLLGVRA GELHGNLTQQ QRLESLKKFK EEQIDVLIAT DVAARGLDIV GVKTVINFVM 480
PITTEHYIHR VGRTARAGRA GISVSLAGEK ERKIVKDIIK NAESTIKNRI IPPEIIEKYR 540
NKLTSLEPEI QNILDEEQAE RQLAKTEQQL SKTERKLLGQ TNERRGWFQT KQQREAEKDR 600
LALTTGDEDK ASGGKGKGKT AGKRKRPEYG GDGEDGPPVK DLEAKRNKKK KEEPRKKTPE 660
QLAKERAMKE IEKVSLVRAK MAKLRKRPGK LGAATEVHRS GASDGKPKRR GGQSAFTNDL 720
TDVSRGGALR LRSEANRHKK MTKIAAKKKA SSVKLTNKAG KNKFNKGKNF GGPRHAKKDK 780
KK 782 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
 GO:0042254; P:ribosome biogenesis; NAS:FlyBase. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000629; RNA-helicase_DEAD-box_CS.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS00039; DEAD_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS