CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Conserved oligomeric Golgi complex subunit 6 
Protein Synonyms/Alias
 COG complex subunit 6; Component of oligomeric Golgi complex 6 
Gene Name
 COG6 
Gene Synonyms/Alias
 KIAA1134 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
126TSRLQAAKEQTQDLIubiquitination[1]
138DLIVKTTKLQSESQKubiquitination[1]
145KLQSESQKLEIRAQVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Required for normal Golgi function (By similarity). 
Sequence Annotation
 MOD_RES 28 28 Phosphoserine.
 MOD_RES 31 31 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; Congenital disorder of glycosylation; Disease mutation; Golgi apparatus; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 657 AA 
Protein Sequence
MAEGSGEVVA VSATGAANGL NNGAGGTSAT TCNPLSRKLH KILETRLDND KEMLEALKAL 60
STFFVENSLR TRRNLRGDIE RKSLAINEEF VSIFKEVKEE LESISEDVQA MSNCCQDMTS 120
RLQAAKEQTQ DLIVKTTKLQ SESQKLEIRA QVADAFLSKF QLTSDEMSLL RGTREGPITE 180
DFFKALGRVK QIHNDVKVLL RTNQQTAGLE IMEQMALLQE TAYERLYRWA QSECRTLTQE 240
SCDVSPVLTQ AMEALQDRPV LYKYTLDEFG TARRSTVVRG FIDALTRGGP GGTPRPIEMH 300
SHDPLRYVGD MLAWLHQATA SEKEHLEALL KHVTTQGVEE NIQEVVGHIT EGVCRPLKVR 360
IEQVIVAEPG AVLLYKISNL LKFYHHTISG IVGNSATALL TTIEEMHLLS KKIFFNSLSL 420
HASKLMDKVE LPPPDLGPSS ALNQTLMLLR EVLASHDSSV VPLDARQADF VQVLSCVLDP 480
LLQMCTVSAS NLGTADMATF MVNSLYMMKT TLALFEFTDR RLEMLQFQIE AHLDTLINEQ 540
ASYVLTRVGL SYIYNTVQQH KPEQGSLANM PNLDSVTLKA AMVQFDRYLS APDNLLIPQL 600
NFLLSATVKE QIVKQSTELV CRAYGEVYAA VMNPINEYKD PENILHRSPQ QVQTLLS 657 
Gene Ontology
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0017119; C:Golgi transport complex; IDA:UniProtKB.
 GO:0070085; P:glycosylation; IMP:UniProtKB.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR010490; COG6. 
Pfam
 PF06419; COG6 
SMART
 SM01087; COG6 
PROSITE
  
PRINTS