UniProt Accession

 D6R9S0_HUMAN; D6R9S0 

Genbank Protein ID

 AC079766 

Genbank Nucleotide ID

  

Protein Name

 Deoxycytidylate deaminase 

Protein Synonyms/Alias

  

Gene Name

 DCTD 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	FLSAQRSKDPNSQVG	ubiquitination	[1]
74	WRRTAENKLDTKYPY	acetylation	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 

Functional Description

  

Sequence Annotation

 ACT_SITE 86 86 Proton donor (By similarity).
 METAL 84 84 Zinc; catalytic (By similarity).
 METAL 110 110 Zinc; catalytic (By similarity).
 METAL 113 113 Zinc; catalytic (By similarity).  

Keyword

 Complete proteome; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 119 AA 

Protein Sequence

Gene Ontology

 GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR016192; APOBEC/CMP_deaminase_Zn-bd.
 IPR002125; CMP_dCMP_Zn-bd.
 IPR015517; Cyt_deaminase.
 IPR016193; Cytidine_deaminase-like.
 IPR016473; dCMP_deaminase. 

Pfam

 PF00383; dCMP_cyt_deam_1 

SMART

  

PROSITE

 PS00903; CYT_DCMP_DEAMINASES 

PRINTS