CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024270
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative aminotransferase MSMEG_6286/MSMEI_6121 
Protein Synonyms/Alias
  
Gene Name
 MSMEG_6286, MSMEI_6121 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
339EDRLGESKIASWTDPpupylation[1, 2]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657]
 [2] Proteome-wide identification of mycobacterial pupylation targets.
 Poulsen C, Akhter Y, Jeon AH, Schmitt-Ulms G, Meyer HE, Stefanski A, Stühler K, Wilmanns M, Song YH.
 Mol Syst Biol. 2010 Jul 13;6:386. [PMID: 20631680] 
Functional Description
  
Sequence Annotation
 REGION 102 105 Pyridoxal phosphate binding (By
 REGION 222 225 Pyridoxal phosphate binding (By
 REGION 256 258 Pyridoxal phosphate binding (By
 BINDING 37 37 Substrate; via amide nitrogen (By
 BINDING 72 72 Pyridoxal phosphate (By similarity).
 BINDING 191 191 Pyridoxal phosphate (By similarity).
 CROSSLNK 339 339 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Aminotransferase; Complete proteome; Isopeptide bond; Pyridoxal phosphate; Reference proteome; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 428 AA 
Protein Sequence
MSFQSLGRDD LLAQHELQQR NYAELQAKQL KLDLTRGKPS PEQLDLSNGL LSLPGDGADA 60
YRDGHGTDTR NYGGVQGLPE LRAIFAELLG LPVENLIAGN NASLEMMHDS VVFSLLHGGL 120
DSPRPWSAEP TVKFLCPAPG YDRHFAITES FGIENVPVPI REDGPDVDVI EQLVASDPTI 180
KGIWCVPVYS NPTGATYSTD VIRRLVQMPT AAKDFRLMWD NAYAVHTLTD EFVEPVDVLG 240
LAAAAGNPNR PLVFASTSKI TFAGAGVSFL GASADNIAWY LKHAGKKSIG PDKVNQLRHL 300
RFFGDADGVR RQMQRHRELI APKFALVAEI LEDRLGESKI ASWTDPKGGY FVSLDVWPGT 360
AKRTVALAKD AGIAVTEAGS AFPYRKDPED KNIRIAPTFP SLPDVRDAID GLATCALLAA 420
TEALLGDK 428 
Gene Ontology
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR024551; Aminotran_put.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 
Pfam
 PF12897; Aminotran_MocR 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS