CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028268
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Regulatory particle triple-A ATPase 4 
Protein Synonyms/Alias
  
Gene Name
 Rpt4 
Gene Synonyms/Alias
 CG3455; Dmel_CG3455 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
28RKKLLEHKEIEGRLKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 397 AA 
Protein Sequence
MTVTATPMPD NLRVKALSEY RKKLLEHKEI EGRLKEKREE IKDLTKLYDK SENDLKALQS 60
VGQIVGEVLK QLTEDKFIVK ATNGPRYVVG CRRQLDKAKL KSGTRVALDM TTLTIMRYLP 120
REVDPLVYNM SHEDPGDVTY SAIGGLTDQI RELREVIELP LLNPELFLRV GITPPKGCLL 180
YGPPGTGKTL LARAVASQLD ANFLKVVSSA IVDKYIGESA RLIREMFNYA RDHQPCIIFM 240
DEIDAIGGRR FSEGTSADRE IQRTLMELLN QMDGFDSLGQ VKMIMATNRP DTLDPALLRP 300
GRLDRKIEIP LPNEQARLEI LKIHALKIAK HGEIDYEAIV KLSDNFNGAD LRNVCTEAGL 360
FAIRAEREYV IQEDFMKAVR KVSDNKKLES KLDYKPV 397 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005634; C:nucleus; IDA:FlyBase.
 GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:EC.
 GO:0001163; F:RNA polymerase I regulatory region sequence-specific DNA binding; IDA:FlyBase.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:1901838; P:positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:FlyBase.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase. 
Interpro
 IPR005937; 26S_Psome_P45.
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA 
SMART
 SM00382; AAA 
PROSITE
 PS00674; AAA 
PRINTS