| Tag | Content |
|---|
| CPLM ID | CPLM-018681 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine/threonine-protein phosphatase 4 regulatory subunit 3B |
Protein Synonyms/Alias | SMEK homolog 2 |
Gene Name | Smek2 |
Gene Synonyms/Alias | Kiaa1387; Pp4r3b; Ppp4r3b |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 456 | NMLATTNKTEKSEFL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers (By similarity). |
Sequence Annotation | DOMAIN 1 100 WH1.
MOD_RES 117 117 Phosphoserine (By similarity).
MOD_RES 811 811 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 820 AA |
Protein Sequence | MSDTRRRVKV YTLNEDRQWD DRGTGHVSST YVEELKGMSL LVRAESDGSL LLESKINPNT 60
AYQKQQDTLI VWSEAENYDL ALSFQEKAGC DEIWEKICQV QGKDPSVEVT QDLIDESEEE 120
RFEEMPETSH LIDLPACELS KLEEIADLVT SVLSSPIRRE KLALALENEG YIKKLLQLFQ 180
ACENLENTEG LHHLYEIIRG ILFLNKATLF EVMFSDECIM DVVGCLEYDP ALAQPKRHRE 240
FLTKTAKFKE VIPITDSELR QKIHQTYRVQ YIQDIILPTP SVFEENFLST LTSFIFFNKV 300
EIVSMLQEDE KFLSEVFAQL TDEATDDDKR RELVNFFKEF CAFSQTLQPQ NRDAFFKTLA 360
KLGILPALEI VMGMDDLQVR SAATDIFSYL VEFSPSMVRE FVMQEAQQSD DDVLLINVVI 420
EQMICDTDPE LGGAVQLMGL LRTLIDPENM LATTNKTEKS EFLNFFYNHC MHVLTAPLLT 480
NTSEDKCEKD NMLGSNTTNT ICPDNYQTAQ LLALILELLT FCVEHHTYHI KNYIMNKDLL 540
RRVLVLMNSK HTFLALCALR FMRRIIGLKD EFYNRYITKG NLFEPVINAL LDNGTRYNLL 600
NSAVIELFEF IRVEDIKSLT AHIVENFYKA LESIEYVQTF KGLKTKYEQE KDRQNQKLNS 660
VPSILRSNRF RRDAKALEED EEMWFNEDDD EEGKAVITPV EKSKTEDDFP DSYEKFMETK 720
KAKESEDKEN LPKRASSGGF KFTFSHSPSA TNGTNSTNSK SVVSQTTPAS SNVASSKTTS 780
LATSVTATKG NLVGLVDYPD DEEEDEEEES SPRKRPRLGS 820 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:MGI. GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. GO:0005634; C:nucleus; IDA:MGI. GO:0030289; C:protein phosphatase 4 complex; IDA:MGI. GO:0045722; P:positive regulation of gluconeogenesis; IDA:MGI. GO:0006470; P:protein dephosphorylation; IMP:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |