UniProt Accession

 RL12_MOUSE; P35979; Q9CQK4 

Genbank Protein ID

 L04280; AK002973; AK008347; AK012349; AK012428; BC018321; BC081469 

Genbank Nucleotide ID

 AAA40066.1; BAB22488.1; BAB25619.1; BAB28180.1; BAB28232.1; AAH18321.1; AAH81469.1 

Protein Name

 60S ribosomal protein L12 

Protein Synonyms/Alias

  

Gene Name

 Rpl12 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
48	KVGDDIAKATGDWKG	acetylation	[1]
48	KVGDDIAKATGDWKG	ubiquitination	[2]
54	AKATGDWKGLRITVK	acetylation	[1]
61	KGLRITVKLTIQNRQ	ubiquitination	[2]
83	SASALIIKALKEPPR	ubiquitination	[2]
99	RKKQKNIKHSGNITF	ubiquitination	[2]
130	RELSGTIKEILGTAQ	ubiquitination	[2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Binds directly to 26S ribosomal RNA. 

Sequence Annotation

 MOD_RES 14 14 Phosphotyrosine (By similarity).
 MOD_RES 38 38 Phosphoserine (By similarity).
 MOD_RES 54 54 N6-acetyllysine (By similarity).
 MOD_RES 165 165 Phosphoserine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 

Interpro

 IPR000911; Ribosomal_L11.
 IPR020783; Ribosomal_L11_C.
 IPR020785; Ribosomal_L11_CS.
 IPR020784; Ribosomal_L11_N. 

Pfam

 PF00298; Ribosomal_L11
 PF03946; Ribosomal_L11_N 

SMART

 SM00649; RL11 

PROSITE

 PS00359; RIBOSOMAL_L11 

PRINTS