CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011586
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Siderophore iron transporter ENB1 
Protein Synonyms/Alias
 Enterobactin permease; Siderophore iron transporter ARN4 
Gene Name
 ENB1 
Gene Synonyms/Alias
 ARN4; YOL158C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
15RNDNLDDKSTVCYSEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis. 
Sequence Annotation
  
Keyword
 Complete proteome; Endosome; Ion transport; Iron; Iron transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 606 AA 
Protein Sequence
MLETDHSRND NLDDKSTVCY SEKTDSNVEK STTSGLRRID AVNKVLSDYS SFTAFGVTFS 60
SLKTALLVAL FLQGYCTGLG GQISQSIQTY AANSFGKHSQ VGSINTVKSI VASVVAVPYA 120
RISDRFGRIE CWIFALVLYT IGEIISAATP TFSGLFAGIV IQQFGYSGFR LLATALTGDL 180
SGLRDRTFAM NIFLIPVIIN TWVSGNIVSS VAGNVAPYKW RWGYGIFCII VPISTLILVL 240
PYVYAQYISW RSGKLPPLKL KEKGQTLRQT LWKFADDINL IGVILFTAFL VLVLLPLTIA 300
GGATSKWREG HIIAMIVVGG CLGFIFLIWE LKFAKNPFIP RVYLGDPTIY VALLMEFVWR 360
LGLQIELEYL VTVLMVAFGE STLSAQRIAQ LYNFLQSCTN IVVGIMLHFY PHPKVFVVAG 420
SLLGVIGMGL LYKYRVVYDG ISGLIGAEIV VGIAGGMIRF PMWTLVHAST THNEMATVTG 480
LLMSVYQIGD AVGASIAGAI WTQRLAKELI QRLGSSLGMA IYKSPLNYLK KYPIGSEVRV 540
QMIESYSKIQ RLLIIVSISF AAFNAVLCFF LRGFTVNKKQ SLSAEEREKE KLKIKQQSWL 600
RRVIGY 606 
Gene Ontology
 GO:0033101; C:cellular bud membrane; IDA:SGD.
 GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0015620; F:ferric-enterobactin transmembrane transporter activity; IMP:SGD. 
Interpro
 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS