CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038783
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ade5, isoform B 
Protein Synonyms/Alias
 RH01319p 
Gene Name
 ade5-RA 
Gene Synonyms/Alias
 ade5; Dmel_CG3989 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
57KAHDLAGKAEISNTTacetylation[1]
114LATGSFLKRNVGVPEacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Isomerase; Ligase; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 428 AA 
Protein Sequence
MSTTTTASKG YKLGKVIIEG KTKQVYDLPE QPGLCLLLSK DRITAGDGVK AHDLAGKAEI 60
SNTTNGQVFR LLNEAGIRTA YVKQCGAKAF IARKCQMIPI EWVTRRLATG SFLKRNVGVP 120
EGYRFSPPKQ ETFFKDDANH DPQWSEEQIV SAKFELNGLV IGQDEVDIMR RTTLLVFEIL 180
ERAWQTKNCA LIDMKVEFGI CDDGNIVLAD IIDSDSWRLW PAGDKRLMVD KQVYRNLASV 240
TASDLDTVKR NFIWVAEQLA DIVPKKDHLV VILMGSASDI SHSEKIATSC RSLGLNVELR 300
VSSAHKGPEE TLRIVREYES VMSNLIFVAV AGRSNGLGPV VSGSTNYPVI NCPPVKSDNM 360
QVDVWSSLNL PSGLGCATVL YPEAAALHAA TILGLGNFMV WSKLRVKALN NFITLKKADK 420
ELRGVRNA 428 
Gene Ontology
 GO:0034023; F:5-(carboxyamino)imidazole ribonucleotide mutase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:EC.
 GO:0004639; F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; IEA:EC.
 GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro. 
Interpro
 IPR013816; ATP_grasp_subdomain_2.
 IPR000031; N5-CAIR_Mutase_PurE_dom.
 IPR001636; SAICAR_synth.
 IPR018236; SAICAR_synthetase_CS. 
Pfam
 PF00731; AIRC
 PF01259; SAICAR_synt 
SMART
 SM01001; AIRC 
PROSITE
 PS01057; SAICAR_SYNTHETASE_1 
PRINTS