UniProt Accession

 Q549N0_HUMAN; Q549N0 

Genbank Protein ID

 AF087867; AK314157; CH471078; CH471078; CH471078 

Genbank Nucleotide ID

 AAM10495.1; BAG36842.1; EAW65908.1; EAW65910.1; EAW65911.1 

Protein Name

 Cofilin 2 (Muscle), isoform CRA_a 

Protein Synonyms/Alias

 Cofilin 2 (Muscle), isoform CRA_c; Cofilin isoform; cDNA, FLJ94864, Homo sapiens cofilin 2 (muscle) (CFL2), mRNA 

Gene Name

 CFL2 

Gene Synonyms/Alias

 hCG_21174 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
19	IKVFNDMKVRKSSTQ	ubiquitination	[1]
92	YDATYETKESKKEDL	ubiquitination	[1]
144	VNGLDDIKDRSTLGE	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Actin-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0015629; C:actin cytoskeleton; IEA:InterPro.
 GO:0030042; P:actin filament depolymerization; IEA:InterPro. 

Interpro

 IPR002108; Actin-bd_cofilin/tropomyosin.
 IPR017904; ADF/Cofilin/Destrin.
 IPR027234; Cofilin_1/2. 

Pfam

 PF00241; Cofilin_ADF 

SMART

 SM00102; ADF 

PROSITE

 PS51263; ADF_H 

PRINTS

 PR00006; COFILIN.