CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003001
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 S-adenosylmethionine:tRNA ribosyltransferase-isomerase 
Protein Synonyms/Alias
 Queuosine biosynthesis protein QueA 
Gene Name
 queA 
Gene Synonyms/Alias
 b0405; JW0395 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
77GRKASGGKIEVLVERacetylation[1]
192FDEPLLEKLRAKGVEacetylation[1]
331YKAAVEEKYRFFSYGacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Queuosine biosynthesis; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MRVTDFSFEL PESLIAHYPM PERSSCRLLS LDGPTGALTH GTFTDLLDKL NPGDLLVFNN 60
TRVIPARLFG RKASGGKIEV LVERMLDDKR ILAHIRASKA PKPGAELLLG DDESINATMT 120
ARHGALFEVE FNDERSVLDI LNSIGHMPLP PYIDRPDEDA DRELYQTVYS EKPGAVAAPT 180
AGLHFDEPLL EKLRAKGVEM AFVTLHVGAG TFQPVRVDTI EDHIMHSEYA EVPQDVVDAV 240
LAAKARGNRV IAVGTTSVRS LESAAQAAKN DLIEPFFDDT QIFIYPGFQY KVVDALVTNF 300
HLPESTLIML VSAFAGYQHT MNAYKAAVEE KYRFFSYGDA MFITYNPQAI NERVGE 356 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0051075; F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity; IDA:EcoCyc.
 GO:0008616; P:queuosine biosynthetic process; IMP:EcoCyc.
 GO:0002099; P:tRNA wobble guanine modification; IMP:EcoCyc. 
Interpro
 IPR003699; Queuosine_synth. 
Pfam
 PF02547; Queuosine_synth 
SMART
  
PROSITE
  
PRINTS