CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013180
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ESF1 homolog 
Protein Synonyms/Alias
 ABT1-associated protein 
Gene Name
 Esf1 
Gene Synonyms/Alias
 Abtap 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
147QKMKNSQKPQKIDSEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). 
Sequence Annotation
 MOD_RES 75 75 Phosphoserine.
 MOD_RES 77 77 Phosphoserine.
 MOD_RES 79 79 Phosphoserine.
 MOD_RES 82 82 Phosphoserine.
 MOD_RES 156 156 Phosphoserine.
 MOD_RES 200 200 Phosphoserine (By similarity).
 MOD_RES 290 290 Phosphoserine (By similarity).
 MOD_RES 292 292 Phosphoserine (By similarity).
 MOD_RES 305 305 Phosphothreonine.
 MOD_RES 306 306 Phosphoserine.
 MOD_RES 307 307 Phosphoserine.
 MOD_RES 651 651 Phosphoserine.
 MOD_RES 657 657 Phosphoserine.
 MOD_RES 686 686 Phosphoserine.
 MOD_RES 688 688 Phosphoserine.
 MOD_RES 689 689 Phosphoserine.
 MOD_RES 729 729 Phosphoserine (By similarity).  
Keyword
 Coiled coil; Complete proteome; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 845 AA 
Protein Sequence
MSSKQEIMDD QRFRRVSKDP RFWEMPEKER KVKIDKRFRA MFHDKKFKLN YAVDKRGRPI 60
SHSTTEDLKR FYDLSDSDSD LSDEESKILS QKKAKQKKKQ TKKEAKSIEK PIEEKKKETK 120
KTDQKDSINK HDLNNSERVQ KMKNSQKPQK IDSEISPKKD NEEFLQNKKK KRGTTDLSVE 180
ALPKGKLRTK DSSTSEMVKS STMSSSKAKR EKQSVVPVIM AKDNDGKMPD EDALEEDSDS 240
ASELGSDEES EDEIISDGKT SADEDESEEE DEEEEEDSEE EEEEEEEDES DSGPDLARGK 300
GNVETSSEDE DDLADLFPEE PGFEHAWREL DKDAPRADEI TRRLAVCNMD WDRLKAKDLL 360
ALFNSFKPKG GVVFSVKIYP SEFGKERMKE EQVQGPVELL SIPEDAPEKD WASREKLRDY 420
QFKRLKYYYA VAECDSPETA SKIYEDCDGL EFESSCSFID LRFIPDDITF DDEPKDVALE 480
VDLTAYKPKY FTSAAMGTST VEITWDETDH ERITTLNRKF KKDELLDMDF QAYLASSSED 540
EEEVEEAPEG EEGVNIGEDG KTKKSQKDDE EQIAKYRQLL QVIQEKEKKG KENDMEMEIK 600
WVPGLKESAE EMVKNKLEGK DKLTPWEQFL EKKKEKKRLK KKQKALAEED SEDELPSDVD 660
FNDPYFAEEV KKIGIKKKSM KSAKDSASSE EETDLEKQKA EMALLVMDEE EDSKKHFNYD 720
KIVEHQNLSK KKKKQLMKKK ELVEDDFEVN VSDARFQAMY TSHLFNLDPS DPNFKKTKAM 780
EKILEEKARH RERKEELLIQ AVERAQQDTG KPTQKQPMDP ALSMLIKSVK NKTEQFQARK 840
KQRVK 845 
Gene Ontology
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR012580; NUC153. 
Pfam
 PF08159; NUC153 
SMART
  
PROSITE
  
PRINTS