CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033641
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Atlastin-3 
Protein Synonyms/Alias
  
Gene Name
 ATL3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
266LDKRLQVKEHQHEEIubiquitination[1, 2, 3, 4, 5]
310PDFDGKLKDIAGEFKubiquitination[1]
336NPSKLMEKEINGSKVubiquitination[4, 5]
342EKEINGSKVTCRGLLubiquitination[4]
353RGLLEYFKAYIKIYQubiquitination[4]
357EYFKAYIKIYQGEDLubiquitination[4, 5]
368GEDLPHPKSMLQATAubiquitination[1]
418EEKHCEFKQLALDHFacetylation[5]
418EEKHCEFKQLALDHFubiquitination[2, 4, 5, 6]
434KTKKMGGKDFSFRYQubiquitination[4, 5]
565VGRPSMDKKAQ****ubiquitination[4]
566GRPSMDKKAQ*****ubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [6] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MRTAGRDPVS AGLQFPKDGS TQRPANRARF VPARTRPSPL HPCCFCFEGG GSMLSPQRVA 60
AAASRGADDA MESSNILLQD HIRDLDVVVV SVAGAFRKGK SFILDFMLRY LYSQKESGHS 120
NWLGDPEEPL TGFSWRGGSD PETTGIQIWS EVFTVEKPGG KKVAVVLMDT QGAFDSQSTV 180
KDCATIFALS TMTSSVQIYN LSQNIQEDDL QQLQLFTEYG RLAMDEIFQK PFQTLMFLVR 240
DWSFPYEYSY GLQGGMAFLD KRLQVKEHQH EEIQNVRNHI HSCFSDVTCF LLPHPGLQVA 300
TSPDFDGKLK DIAGEFKEQL QALIPYVLNP SKLMEKEING SKVTCRGLLE YFKAYIKIYQ 360
GEDLPHPKSM LQATAEANNL AAAASAKDIY YNNMEEVCGG EKPYLSPDIL EEKHCEFKQL 420
ALDHFKKTKK MGGKDFSFRY QQELEEEIKE LYENFCKHNG SKNVFSTFRT PAVLFTGIVA 480
LYIASGLTGF IGLEVVAQLF NCMVGLLLIA LLTWGYIRYS GQYRELGGAI DFGAAYVLEQ 540
ASSHIGNSTQ ATVRDAVVGR PSMDKKAQ 568 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP
 PF02841; GBP_C 
SMART
  
PROSITE
  
PRINTS