UniProt Accession

 LYRM4_MOUSE; Q8K215 

Genbank Protein ID

 AK050553; BC034664; BC080772 

Genbank Nucleotide ID

 BAC34321.1; AAH34664.1; AAH80772.1 

Protein Name

 LYR motif-containing protein 4 

Protein Synonyms/Alias

  

Gene Name

 Lyrm4 

Gene Synonyms/Alias

 Isd11 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
21	RAMMRESKHFSAYNY	acetylation	[1]
47	FRENKNVKDPVEIQA	acetylation	[2]
47	FRENKNVKDPVEIQA	succinylation	[2]

Reference

 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Required for nuclear and mitochondrial iron-sulfur protein biosynthesis (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Mitochondrion; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 91 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 

Interpro

 IPR008011; Complex1_LYR. 

Pfam

 PF05347; Complex1_LYR 

SMART

  

PROSITE

  

PRINTS