CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029422
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ78476, highly similar to Homo sapiens WD repeat and HMG-box DNA binding protein 1 (WDHD1), transcript variant 1, mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
811RKLILAQKLSELAVEubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1129 AA 
Protein Sequence
MPATRKPMRY GHTEGHTEVC FDDSGSFIVT CGSDGDVRIW EDLDDDDPKF INVGEKAYSC 60
ALKSGKLVTA FSNNTIQVHT FPEGVPDGIL TRFTTNANHV VFNGDGTKIA AGSSDFLVKI 120
VDVMDSSQQK TFRGHDAPVL SLSFDPKDIF LASASCDGSV RVWQISDQTC AISWPLLQKC 180
NDVINAKSIC RLAWQPKSGK LLAIPVEKSV KLYRRESWSH QFDLSDNFIS QTLNIVTWSP 240
CGQYLAAGSI NGLIIVWNVE TKDCMERVKH EKGYAICGLA WHPTCGRISY TDAEGNLGLL 300
ENVCDPSGKT SSSKVSSRVE KDYNDLFDGD DMSNAGDFLN DNAVEIPSFS KGIINDDEDD 360
EDLMMASGRP RQRSHILEDD ENSVDISMLK TGSSLLKEEE EDGQEGSIHN LPLVTSQRPF 420
YDGPMPTPRQ KPFQSGSTPL HLTHRFMVWN SIGIIRCYND EQDNAIDVEF HDTSIHHATH 480
LSNTLNYTIA DLSHEAILLA CESTDELASK LHCLHFSSWD SSKEWIIDLP QNEDIEAICL 540
GQGWAAAATS ALLLRLFTIG GVQKEVFSLA GPVVSMAGHG EQLFIVYHRG TGFDGDQCLG 600
VQLLELGKKK KQILHGDPLP LTRKSYLAWI GFSAEGTPCY VDSEGIVRML NRGLGNTWTP 660
ICNTREHCKG KSDHYWVVGI HENPQQLRCI PCKGSRFPPT LPRPAVAILS FKLPYCQIAT 720
EKGQMEEQFW RSVIFHNHLD YLAKNGYEYE ESTKNQATKE QQELLMKMLA LSCKLEREFR 780
CVELADLMTQ NAVNLAIKYA SRSRKLILAQ KLSELAVEKA AELTATQVEE EEEEEDFRKK 840
LNAGYSNTAT EWSQPRFRNQ VEEDAEDSGE ADDEEKPEIH KPGQNSFSKS TNSSDVSAKS 900
GAVTFSSQGR VNPFKVSASS KEPAMSMNSA RSTNILDNMG KSSKKSTALS RTTNNEKSPI 960
IKPLIPKPKP KQASAASYFQ KRNSQTNKTE EVKEENLKNV LSETPAICPP QNTENQRPKT 1020
GFQMWLEENR SNILSDNPDF SDEADIIKEG MIRFRVLSTE ERKVWANKAK GETASEGTEA 1080
KKRKRVVDES DETENQEEKA KENLNLSKKQ KPLDFSTNQK LSAFAFKQE 1129 
Gene Ontology
  
Interpro
 IPR022100; DUF3639.
 IPR009071; HMG_box_dom.
 IPR013979; TIF_beta_prop-like.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF12341; DUF3639
 PF08662; eIF2A
 PF00505; HMG_box
 PF00400; WD40 
SMART
 SM00398; HMG
 SM00320; WD40 
PROSITE
 PS50118; HMG_BOX_2
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS