| Tag | Content |
|---|
| CPLM ID | CPLM-001419 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Short-chain dehydrogenase/reductase 3 |
Protein Synonyms/Alias | Retinal short-chain dehydrogenase/reductase 1; retSDR1 |
Gene Name | Dhrs3 |
Gene Synonyms/Alias | Rsdr1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 113 | MAKAVREKVGDITIL | ubiquitination | [1] | | 142 | SDDDALLKSQHVNTL | ubiquitination | [1] | | 242 | PNLFPPLKPETVARR | ubiquitination | [1] | | 299 | YTCMNTFKGRT**** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH (By similarity). |
Sequence Annotation | ACT_SITE 188 188 Proton acceptor (By similarity).
BINDING 175 175 Substrate (By similarity). |
Keyword | Alternative splicing; Complete proteome; Membrane; NADP; Oxidoreductase; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 302 AA |
Protein Sequence | MVWKWLGALV VFPLQMIYLV TKAAVGMVLP PKLRDLSRES VLITGGGRGI GRHLAREFAE 60
RGARKIVLWG RTEKCLKETT EEIRQMGTEC HYFICDVGNR EEVYQMAKAV REKVGDITIL 120
VNNAAVVHGK SLMDSDDDAL LKSQHVNTLG QFWTTKAFLP RMLELQNGHI VCLNSVLALS 180
AIPGAIDYCT SKASAFAFME SLTLGLLDCP GVSATTVLPF HTSTEMFQGM RVRFPNLFPP 240
LKPETVARRT VDAVQQNQAL LLLPWTMNIL IILKSILPQA ALEEIHRFSG TYTCMNTFKG 300
RT 302 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |