UniProt Accession

 TIM14_YEAST; Q07914; D6VY10 

Genbank Protein ID

 Z73180; AY558196; BK006945 

Genbank Nucleotide ID

 CAA97530.1; AAS56522.1; DAA09326.1 

Protein Name

 Mitochondrial import inner membrane translocase subunit TIM14 

Protein Synonyms/Alias

 Presequence translocated-associated motor subunit PAM18 

Gene Name

 PAM18 

Gene Synonyms/Alias

 TIM14; YLR008C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
101	KSTTAFLKGGFDPKM	acetylation	[1]
144	MLANHPDKGGSPFLA	acetylation	[1]
158	ATKINEAKDFLEKRG	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1). 

Sequence Annotation

 DOMAIN 112 168 J.  

Keyword

 3D-structure; Chaperone; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport; Reference proteome; Translocation; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 168 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0001405; C:presequence translocase-associated import motor; IDA:SGD.
 GO:0001671; F:ATPase activator activity; IMP:SGD.
 GO:0051082; F:unfolded protein binding; ISS:SGD.
 GO:0030150; P:protein import into mitochondrial matrix; IMP:SGD. 

Interpro

 IPR001623; DnaJ_domain. 

Pfam

 PF00226; DnaJ 

SMART

 SM00271; DnaJ 

PROSITE

 PS00636; DNAJ_1
 PS50076; DNAJ_2 

PRINTS