UniProt Accession

 F6QQQ6_MOUSE; F6QQQ6 

Genbank Protein ID

 AC164433 

Genbank Nucleotide ID

  

Protein Name

 Protein arginine N-methyltransferase 5 

Protein Synonyms/Alias

  

Gene Name

 Prmt5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
24	RWLGEPIKAAILPTS	ubiquitination	[1]
37	TSIFLTNKKGFPVLS	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 204 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003682; F:chromatin binding; IMP:MGI.
 GO:0008168; F:methyltransferase activity; ISO:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.
 GO:0035246; P:peptidyl-arginine N-methylation; ISO:MGI. 

Interpro

 IPR025799; Arg_MeTrfase.
 IPR007857; Arg_MeTrfase_PRMT5. 

Pfam

 PF05185; PRMT5 

SMART

  

PROSITE

  

PRINTS