CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024138
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vesicle-associated membrane protein-associated protein A 
Protein Synonyms/Alias
 VAMP-A; VAMP-associated protein A; VAP-A; 33 kDa VAMP-associated protein; VAP-33 
Gene Name
 Vapa 
Gene Synonyms/Alias
 Vap33 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
117EAVWKEAKPDELMDSacetylation[1]
125PDELMDSKLRCVFEMacetylation[1]
161KQDGPLPKPHSVSLNacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May play a role in vesicle trafficking. 
Sequence Annotation
 DOMAIN 14 131 MSP.
 MOD_RES 125 125 N6-acetyllysine (By similarity).  
Keyword
 3D-structure; Acetylation; Coiled coil; Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 249 AA 
Protein Sequence
MASASGAMAK HEQILVLDPP SDLKFKGPFT DVVTTNLKLQ NPSDRKVCFK VKTTAPRRYC 60
VRPNSGVIDP GSIVTVSVML QPFDYDPNEK SKHKFMVQTI FAPPNISDME AVWKEAKPDE 120
LMDSKLRCVF EMPNENDKLN DMEPSKAVPL NASKQDGPLP KPHSVSLNDT ETRKLMEECK 180
RLQGEMMKLS EENRHLRDEG LRLRKVAHSD KPGSTSAVSF RDNVTSPLPS LLVVIAAIFI 240
GFFLGKFIL 249 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; IDA:BHF-UCL.
 GO:0005874; C:microtubule; IEA:Compara.
 GO:0046982; F:protein heterodimerization activity; IDA:RGD.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0008219; P:cell death; IMP:UniProtKB.
 GO:0031175; P:neuron projection development; IMP:UniProtKB.
 GO:0070972; P:protein localization to endoplasmic reticulum; ISS:UniProtKB. 
Interpro
 IPR000535; Major_sperm.
 IPR008962; PapD-like.
 IPR016763; Vesicle-associated_membrane. 
Pfam
 PF00635; Motile_Sperm 
SMART
  
PROSITE
 PS50202; MSP 
PRINTS